Bi-continuous Mg-Ti interpenetrating-phase composite as a partially degradable and bioactive implant material
文献类型：期刊论文
| 作者 | Dou, Chenxi2,3; Zhang, Mingyang3,4; Ren, Dechun3; Ji, Haibin3; Yi, Zhe2; Wang, Shaogang3; Liu, Zengqian3,4; Wang, Qiang2; Zheng, Yufeng1; Zhang, Zhefeng3,4 |
| 刊名 | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2023-05-20 |
| 卷号 | 146页码:211-220 |
| ISSN号 | 1005-0302 |
| 关键词 | Mg-Ti composite Interpenetrating-phase architecture Implant Bioactivity Degradation Strength |
| DOI | 10.1016/j.jmst.2022.11.011 |
| 通讯作者 | Yi, Zhe(zheyi@cmu.edu.cn) ; Liu, Zengqian(zengqianliu@imr.ac.cn) ; Wang, Qiang(mfqwang@cmu.edu.cn) |
| 英文摘要 | Mg (and Mg alloys) and Ti (and Ti alloys) are two important classes of metallic implant materials which are respectively completely degradable and non-degradable after implantation. Making composites com-posed of them offers the promise for combining their property advantages for bone repair. Here, we present a Mg-Ti composite fabricated by pressureless infiltration of pure Mg melt into 3D printed Ti scaf-fold, and demonstrate a potential of the composite for use as new partially degradable and bioactive implant materials. The composite has such architecture that the Mg and Ti phases are topologically bi-continuous and mutually interspersed in 3D space, and exhibits several advantages over its constituents, such as higher strengths than as-cast pure Mg and Ti scaffold along with lower Young's modulus than dense Ti. Additionally, the degradation of Mg phase may induce the formation and ingrowth of new bone tissues into the Ti scaffold to form mechanical interlocking between them; in this process, the Ti scaffold provides constant support and Young's modulus adaptively decreases toward that of bone. Despite the accelerated corrosion than pure Mg, the composite remains non-cytotoxic and does not cause obvious adverse reactions after implantation as revealed by in vitro and in vivo experiments. This study may offer a new possibility for combining mechanical durability and bioactivity in implant materials, and allow for customized and targeted design of the implant.(c) 2022 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| 资助项目 | National Key R&D Program of China[2020YFA0710404] ; National Natural Sci-ence Foundation of China[51871216] ; National Natural Sci-ence Foundation of China[52173269] ; Youth Innovation Promotion Association CAS |
| WOS研究方向 | Materials Science ; Metallurgy & Metallurgical Engineering |
| 语种 | 英语 |
| 出版者 | JOURNAL MATER SCI TECHNOL |
| WOS记录号 | WOS:000913755000001 |
| 资助机构 | National Key R&D Program of China ; National Natural Sci-ence Foundation of China ; Youth Innovation Promotion Association CAS |
| 源URL | [http://ir.imr.ac.cn/handle/321006/175221]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Yi, Zhe; Liu, Zengqian; Wang, Qiang |
| 作者单位 | 1.Peking Univ, Sch Mat Sci & Engn, Beijing 100871, Peoples R China 2.China Med Univ, Sch & Hosp Stomatol, Liaoning Prov Key Lab Oral Dis, Shenyang 110001, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shi Changxu Innovat Ctr Adv Mat, Shenyang 110016, Peoples R China 4.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Peoples R China 5.ShanghaiTech Univ, Ctr Adapt Syst Engn, Sch Creat & Art, Shanghai 201210, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dou, Chenxi,Zhang, Mingyang,Ren, Dechun,et al. Bi-continuous Mg-Ti interpenetrating-phase composite as a partially degradable and bioactive implant material[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2023,146:211-220. |
| APA | Dou, Chenxi.,Zhang, Mingyang.,Ren, Dechun.,Ji, Haibin.,Yi, Zhe.,...&Yang, Rui.(2023).Bi-continuous Mg-Ti interpenetrating-phase composite as a partially degradable and bioactive implant material.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,146,211-220. |
| MLA | Dou, Chenxi,et al."Bi-continuous Mg-Ti interpenetrating-phase composite as a partially degradable and bioactive implant material".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 146(2023):211-220. |
入库方式： OAI收割
来源：金属研究所
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