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Construction of Chalcogenated Methylene Chroman-3-ones via Palladium-Catalyzed Carbocyclization

文献类型：期刊论文

作者Liu, Min2; Huang, Jiaxin2,3; Xu, Hui2; Dai, Hui-Xiong1,2,3
刊名JOURNAL OF ORGANIC CHEMISTRY
出版日期2023-05-16
卷号88期号:11页码:7070-7074
ISSN号0022-3263
DOI10.1021/acs.joc.3c00341
通讯作者Xu, Hui(xuhui2018@simm.ac.cn) ; Dai, Hui-Xiong(hxdai@simm.ac.cn)
英文摘要Wereport herein the synthesis of exo-chalcogenated methylene chroman-3-onesvia palladium-catalyzed intramolecular acyl-chalcogenation of alkynewith thio- and selenoesters. Chalcogen containing tetrasubstitutedalkenes are obtained stereoselectively. This protocol tolerates variousfunctional groups and heterocycles, affording the chroman-3-one productsin moderate-to-good yields.
WOS关键词EFFICIENT SYNTHESIS ; THIOESTERS ; BOND ; ORGANOSELENIUM ; CHEMISTRY ; INSERTION ; ALKYNES ; ACYL
资助项目Shanghai Institute of Materia Medica ; Chinese Academy of Sciences ; National Natural Science Foundation of China[22171276] ; National Natural Science Foundation of China[21920102003] ; Youth Innovation Promotion Association CAS[2014229] ; Youth Innovation Promotion Association CAS[2018293] ; Institutes for Drug Discovery and Development, Chinese Academy of Sciences[CASIMM0120163006] ; Science and Technology Commission of Shanghai Municipality[17JC1405000] ; Science and Technology Commission of Shanghai Municipality[21ZR1475400] ; Science and Technology Commission of Shanghai Municipality[18431907100] ; Program of Shanghai Academic Research Leader[19XD1424600] ; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2018ZX09711002-006]
WOS研究方向Chemistry
语种英语
出版者AMER CHEMICAL SOC
WOS记录号WOS:001013682500001
源URL[http://119.78.100.183/handle/2S10ELR8/306296]  
专题新药研究国家重点实验室
通讯作者Xu, Hui; Dai, Hui-Xiong
作者单位1.Hangzhou Inst Adv Study, Sch Pharmaceut Sci & Technol, Hangzhou 310024, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, State Key Lab Drug Res, Shanghai 201203, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Min,Huang, Jiaxin,Xu, Hui,et al. Construction of Chalcogenated Methylene Chroman-3-ones via Palladium-Catalyzed Carbocyclization[J]. JOURNAL OF ORGANIC CHEMISTRY,2023,88(11):7070-7074.
APA Liu, Min,Huang, Jiaxin,Xu, Hui,&Dai, Hui-Xiong.(2023).Construction of Chalcogenated Methylene Chroman-3-ones via Palladium-Catalyzed Carbocyclization.JOURNAL OF ORGANIC CHEMISTRY,88(11),7070-7074.
MLA Liu, Min,et al."Construction of Chalcogenated Methylene Chroman-3-ones via Palladium-Catalyzed Carbocyclization".JOURNAL OF ORGANIC CHEMISTRY 88.11(2023):7070-7074.

入库方式： OAI收割

来源：上海药物研究所

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