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Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig

文献类型：期刊论文

作者Su, Ming-Zhi1; Zhou, Zhen-Fang2; Guo, Yue-Wei1,2
刊名CHEMISTRY & BIODIVERSITY
出版日期2023-07-24
页码5
关键词Xylocarpus granatum mangrove plant protolimonoid apotirucallane glabretal
ISSN号1612-1872
DOI10.1002/cbdv.202300692
通讯作者Su, Ming-Zhi(mzsu@baridd.ac.cn) ; Guo, Yue-Wei(ywguo@simm.ac.cn)
英文摘要Two new compounds including one apotirucallane protolimonoid, xylogranatriterpin A (1), and one glabretal protolimonoid, xylocarpusin A (2), along with three known related compounds were isolated from the twigs and leaves of the Chinese mangrove Xylocarpus granatum. The apotirucallane xylogranatriterpin A (1) bears an unprecedented 24-ketal carbon connecting ring E with an epoxide ring. The structures of new compounds were elucidated by extensive spectroscopic analysis and by comparison of the spectroscopic data with those reported in the literatures. Plausible biosynthetic pathway to xylogranatriterpin A (1) was also proposed. None of them showed cytotoxic, neuroprotective, or protein tyrosine phosphatase 1B (PTP1B) inhibitory activity.
WOS关键词CHEMICAL-CONSTITUENTS ; LIMONOIDS ; TRITERPENOIDS ; SKELETON
资助项目National Key Research and Development Program of China[2022YFC2804100] ; National Natural Science Foundation of China[81991521]
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
语种英语
WOS记录号WOS:001032175100001
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/306698]  
专题新药研究国家重点实验室
通讯作者Su, Ming-Zhi; Guo, Yue-Wei
作者单位1.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Zu Chong Zhi Rd 555, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Su, Ming-Zhi,Zhou, Zhen-Fang,Guo, Yue-Wei. Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig[J]. CHEMISTRY & BIODIVERSITY,2023:5.
APA Su, Ming-Zhi,Zhou, Zhen-Fang,&Guo, Yue-Wei.(2023).Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig.CHEMISTRY & BIODIVERSITY,5.
MLA Su, Ming-Zhi,et al."Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig".CHEMISTRY & BIODIVERSITY (2023):5.

入库方式： OAI收割

来源：上海药物研究所

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