Undescribed steroidal alkaloids from the bulbs of Fritillaria sinica
文献类型：期刊论文
| 作者 | Li, Jia-yuan1; Wu, Shi-fei1; An, Ya-ling1,2; Yao, Chang-liang1; Yao, Shuai1; Huang, Yong1; Wei, Wen -long1; Zhang, Jian-qing1; Bi, Qi-rui1; Qu, Hua1 |
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2023-09-01 |
| 卷号 | 213页码:11 |
| 关键词 | Fritillaria sinica Liliaceae Zhonghuabeimu Steroidal alkaloid derivatives Anti -cancer effect Anti -oxidation Anti -inflammation |
| ISSN号 | 0031-9422 |
| DOI | 10.1016/j.phytochem.2023.113768 |
| 通讯作者 | Guo, De-an(daguo@simm.ac.cn) |
| 英文摘要 | Eight undescribed steroidal alkaloid derivatives, including three cevanine-type isosteroidal alkaloids (two N -oxide glycosides and one D-ring aromatization) (1-3), one verazine-type steroidal alkaloid derivative (4), three solanidine-type steroidal alkaloid glycosides (5-7), and one veratramine-type analogue (8), along with three known compounds (9-11) were isolated from the bulbs of Fritillaria sinica. Their structures were elucidated by comprehensive analysis of spectroscopic data, acidic hydrolysis, and X-ray crystal diffractions. In the in vitro bioassay, the anti-cancer effect, anti-oxidation and anti-inflammatory activities for the isolates were evaluated at a concentration of 10 & mu;M. |
| WOS关键词 | ISOSTEROIDAL ALKALOIDS ; ELUCIDATION |
| 资助项目 | Qi-Huang Chief Scientist Project of National Administration of Traditional Chinese Medicine ; Key Program of National Natural Science Foundation of China[82130111] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:001032620100001 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/306791]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Guo, De-an |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Engn Res Ctr TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, 501 Haike Rd, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Jia-yuan,Wu, Shi-fei,An, Ya-ling,et al. Undescribed steroidal alkaloids from the bulbs of Fritillaria sinica[J]. PHYTOCHEMISTRY,2023,213:11. |
| APA | Li, Jia-yuan.,Wu, Shi-fei.,An, Ya-ling.,Yao, Chang-liang.,Yao, Shuai.,...&Guo, De-an.(2023).Undescribed steroidal alkaloids from the bulbs of Fritillaria sinica.PHYTOCHEMISTRY,213,11. |
| MLA | Li, Jia-yuan,et al."Undescribed steroidal alkaloids from the bulbs of Fritillaria sinica".PHYTOCHEMISTRY 213(2023):11. |
入库方式： OAI收割
来源：上海药物研究所
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