Preparation and characterization of monodisperse superparamagnetic poly(vinyl alcohol) beads by reverse spray suspension Crosslinking
文献类型：期刊论文
| 作者 | Yang, Chengli1,2; Guan, Yueping1,3; Xing, Jianmin1; Shan, Guobin1; Liu, Huizhou1 |
| 刊名 | JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
 |
| 出版日期 | 2008 |
| 卷号 | 46期号:1页码:203-210 |
| 关键词 | biodegradable crosslinking magnetic polymers poly(vinyl alcohol) beads protein separation superparamagnetic |
| ISSN号 | 0887-624X |
| 其他题名 | J. Polym. Sci. Pol. Chem. |
| 中文摘要 | A novel protocol for preparing magnetic poly(vinyl alcohol) (PVA) beads by reverse spray suspension crosslinking was reported. The hydrophilic Fe3O4 nanoparticles were mixed with PVA, glutaraldehyde, and water to form aqueous phase. Then the aqueous phase was sprayed into vegetable oil by a pressure of nitrogen gas to form water in oil (W/O) suspension. The magnetic PVA beads were obtained in the presence of hydrochloric acid catalyst. It was found that the magnetic PVA beads obtained good properties when the PVA concentration was 10%, and the oil phase temperature was controlled at 40 degrees C. The mechanical stirring has little impact on the size of magnetic PVA beads in the process of reverse spray suspension crosslinking. The Cibacron Blue (CB) was coupled on the surface of magnetic PVA beads by surface chemical reaction. The morphology, size, and magnetic properties of the magnetic PVA beads were examined by scanning electron microscopy, laser diffraction, and vibrating sample magnetometer, respectively. Compared with the stirring method, it was found that the size of magnetic PVA beads was monodisperse and their saturation magnetization was much higher. Fourier transform infrared and X-ray photoelectron spectroscopy experimental results proved that CB molecules were covalently immobilized onto the surface of the magnetic PVA beads. Meanwhile, the protein affinity separation experiments demonstrated that the magnetic PVA beads can potentially be used as a carrier for large-scale protein separation. (c) 2007 Wiley Periodicals, Inc. |
| 英文摘要 | A novel protocol for preparing magnetic poly(vinyl alcohol) (PVA) beads by reverse spray suspension crosslinking was reported. The hydrophilic Fe3O4 nanoparticles were mixed with PVA, glutaraldehyde, and water to form aqueous phase. Then the aqueous phase was sprayed into vegetable oil by a pressure of nitrogen gas to form water in oil (W/O) suspension. The magnetic PVA beads were obtained in the presence of hydrochloric acid catalyst. It was found that the magnetic PVA beads obtained good properties when the PVA concentration was 10%, and the oil phase temperature was controlled at 40 degrees C. The mechanical stirring has little impact on the size of magnetic PVA beads in the process of reverse spray suspension crosslinking. The Cibacron Blue (CB) was coupled on the surface of magnetic PVA beads by surface chemical reaction. The morphology, size, and magnetic properties of the magnetic PVA beads were examined by scanning electron microscopy, laser diffraction, and vibrating sample magnetometer, respectively. Compared with the stirring method, it was found that the size of magnetic PVA beads was monodisperse and their saturation magnetization was much higher. Fourier transform infrared and X-ray photoelectron spectroscopy experimental results proved that CB molecules were covalently immobilized onto the surface of the magnetic PVA beads. Meanwhile, the protein affinity separation experiments demonstrated that the magnetic PVA beads can potentially be used as a carrier for large-scale protein separation. (c) 2007 Wiley Periodicals, Inc. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Polymer Science |
| 研究领域[WOS] | Polymer Science |
| 关键词[WOS] | METHACRYLATE) MICROSPHERES ; MAGNETIC NANOPARTICLES ; PROTEIN ADSORPTION ; POLYMERIZATION ; PARTICLES ; CARRIERS |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000251980900021 |
| 公开日期 | 2013-10-08 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/2892]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Lab Seprat Sci & Engn, Beijing 100080, Peoples R China 2.Georgetown Univ, Med Ctr, Lombardi Comprehens Canc Ctr, Dept Oncol, Washington, DC 20057 USA 3.Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Chengli,Guan, Yueping,Xing, Jianmin,et al. Preparation and characterization of monodisperse superparamagnetic poly(vinyl alcohol) beads by reverse spray suspension Crosslinking[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,2008,46(1):203-210. |
| APA | Yang, Chengli,Guan, Yueping,Xing, Jianmin,Shan, Guobin,&Liu, Huizhou.(2008).Preparation and characterization of monodisperse superparamagnetic poly(vinyl alcohol) beads by reverse spray suspension Crosslinking.JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,46(1),203-210. |
| MLA | Yang, Chengli,et al."Preparation and characterization of monodisperse superparamagnetic poly(vinyl alcohol) beads by reverse spray suspension Crosslinking".JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY 46.1(2008):203-210. |
入库方式： OAI收割
来源：过程工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。