The study of wave characteristic changes is critical for understanding the role of wave erosion in the shoreline erosion of reservoirs and its subsequent impact on environmental pollution. This study utilizes RBRvirtuoso Dwave-pressure-based wave gauges to make in situ observations of the nearshore significant wave height (SWH) in the Three Gorges Reservoir. The differential and impact factors affecting the SWH under varying water levels, in the main and tributary streams, and shoreline sections are analyzed. This research also investigates the alteration of the frequency distribution of the SWH. The findings indicate that the average SWH increases as the water level increases, reaching 1.2 cm, 1.5 cm, and 1.9 cm for water levels of 150 m, 165 m, and 175 m, respectively, with a SWH frequency distribution curve that becomes increasingly smooth. The average SWH in the mainstream is 2.9 times larger than that in the tributaries, with the former having a smoother frequency distribution curve. The average SWHs in different shoreline sections are inconsistent at the same water level, with the Badong (downstream) section near the Three Gorges Dam exhibiting a significantly higher average SWH than the Zhongxian (midstream) section further from the dam. When shipping activities intensify, there is often a marked increase in the magnitude of the SWH. The SWH in narrower reservoir sections is significantly greater than that in wider sections, with average measurements of 2.2 cm and 1.4 cm, respectively. Fluctuations of the water level, shipping activities, and other factors in the Three Gorges Reservoir have a significant impact on the alteration of the nearshore SWH, and changes in the SWH from low to high water levels may result in changes in both the spatial and temporal patterns of shoreline erosion. These alterations can, in turn, affect sediment and nutrient transport, potentially exacerbating environmental pollution issues.