Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder
文献类型：期刊论文
| 作者 | Huang, Zhi-Xin4,5,6; Wang, Qizhang3; Lei, Shasha5; Zhang, Wenli6; Huang, Ying6; Zhang, Caiping4; Zhang, Xiangyang1,2
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| 刊名 | SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
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| 出版日期 | 2023-10-13 |
| 页码 | 9 |
| 关键词 | Anxiety disorders Depression Mood disorders Suicide Psychotic disorder |
| ISSN号 | 0933-7954 |
| DOI | 10.1007/s00127-023-02572-3 |
| 通讯作者 | Zhang, Xiangyang(zhangxy@psych.ac.cn) |
| 英文摘要 | Early identification of high-risk patients with Major depressive disorder (MDD) having suicide attempts (SAs) is essential for timely targeted and tailored psychological interventions and medications. This study aimed to develop and validate a web-based dynamic nomogram as a personalized predictor of SA in MDD patients. A dynamic nomogram was developed using data collected from 1718 patients in China. The dynamic model was established based on a machine learning-based regression technique in the training cohort. We validated the nomogram internally using 1000 bootstrap replications. The nomogram performance was assessed using estimates of discrimination (via the concordance index) and calibration (calibration plots). The nomogram incorporated five predictors, including Hamilton anxiety rating scale (odds ratio [OR]: 1.255), marital status (OR: 0.618), clinical global impressions (OR: 2.242), anti-thyroid peroxidase antibodies (OR: 1.002), and systolic pressure levels (OR: 1.037). The model demonstrated good overall discrimination (Harrell's C-index = 0.823). Using decision curve analysis, this model also demonstrated good clinical applicability. An online web server was constructed (https://odywong.shinyapps.io/PRSM/) to facilitate the use of the nomogram. Based on these results, our study developed a nomogram to predict SA in MDD patients. The application of this nomogram may help for patients and clinicians to make decisions. |
| 收录类别 | SCI |
| WOS关键词 | MARITAL-STATUS ; CHOLESTEROL ; METAANALYSIS ; INDIVIDUALS ; BIPOLAR |
| 资助项目 | We sincerely thank all the participants in this study for their support and cooperation. |
| WOS研究方向 | Psychiatry |
| 语种 | 英语 |
| WOS记录号 | WOS:001083645200001 |
| 出版者 | SPRINGER HEIDELBERG |
| 资助机构 | We sincerely thank all the participants in this study for their support and cooperation. |
| 源URL | [http://ir.psych.ac.cn/handle/311026/46242]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Zhang, Xiangyang |
| 作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, 16 Lincui Rd, Beijing 100101, Peoples R China 3.Shenzhen Hosp Integrated Tradit Chinese & Western, Dept Neurol, Shenzhen 518104, Guangdong, Peoples R China 4.Guangdong Med Univ, Zhanjiang, Guangdong, Peoples R China 5.Jinan Univ, Fac Med Sci, Guangzhou, Guangdong, Peoples R China 6.Guangdong Second Prov Gen Hosp, Dept Neurol, Guangzhou, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Zhi-Xin,Wang, Qizhang,Lei, Shasha,et al. Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder[J]. SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY,2023:9. |
| APA | Huang, Zhi-Xin.,Wang, Qizhang.,Lei, Shasha.,Zhang, Wenli.,Huang, Ying.,...&Zhang, Xiangyang.(2023).Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder.SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY,9. |
| MLA | Huang, Zhi-Xin,et al."Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder".SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY (2023):9. |
入库方式： OAI收割
来源：心理研究所
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