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Gender differences and clinical correlates in the age of the first hospitalization in patients with drug-naïve schizophrenia in China: a cross-sectional study

文献类型：期刊论文

作者Luo, Guoshuai2; Li, Meijuan2; Qiu, Yuying2; Yao, Cong2; Zhang, Xiangyang1; Li, Jie2
刊名EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
出版日期2023-10-13
页码10
ISSN号0940-1334
关键词Gender differences Schizophrenia Hospitalization Drug-na & iuml ve
DOI10.1007/s00406-023-01697-5
通讯作者Zhang, Xiangyang(zhangxy@psych.ac.cn) ; Li, Jie(jieli@tmu.edu.cn)
英文摘要Gender differences in the onset age of schizophrenia have been reported in many studies, but differences in the age of the first hospitalization and associated factors have not been explored. The present study investigated gender differences and clinical correlates in the age of the first hospitalization in drug-na & iuml;ve schizophrenia (DNS). A total of 144 DNS patients and 67 health controls were included. Demographic information, duration of untreated psychosis (DUP), Positive and Negative Symptom Scale (PANSS) scores, the Brief Psychiatric Rating Scale (BPRS) scores, Global Assessment of Functioning (GAF) scores, and MATRICS Consensus Cognitive Battery (MCCB) scores were collected and analyzed. The age of the first hospitalization was significantly earlier in males than in females (P < 0.01). In addition, there were significant differences in the age of the first hospitalization in terms of marital status, occupation, family ranking, suicide attempt, and place of residence (all P < 0.05). After Bonferroni correction, only DUP had a positive correlation with the age of the first hospitalization (P-Bonferroni < 0.05/6 = 0.0083). Multivariate linear regression analysis showed that gender (beta = 0.141, t = 2.434, P = 0.016), marital status (beta = 0.219, t = 3.463, P = 0.001), family ranking (beta = 0.300, t = 4.918, P < 0.001), suicide attempt (beta = 0.348, t = 5.549, P < 0.001), and DUP (beta = 0.190, t = 2.969, P < 0.004) positively predicted the age of the first hospitalization. The age of the first hospitalization in male DNS was earlier than in females. In addition, gender, marital status, suicide attempt, DUP, and family rank were independent risk factors for the age of the first hospitalization.
收录类别SCI
WOS关键词SEX-DIFFERENCES ; UNTREATED PSYCHOSIS ; 1ST-EPISODE ; PREVALENCE ; MORTALITY ; DURATION ; MARRIAGE ; CHILDREN ; SUICIDE ; RATES
资助项目We extend our gratitude to Yongping Zhao, Shu Yang, Ying Gao, Siying Kong, and Xiaoxiao Sun from the Tianjin Anding Hospital for their assistance in data collection.
WOS研究方向Neurosciences & Neurology ; Psychiatry
语种英语
出版者SPRINGER HEIDELBERG
WOS记录号WOS:001084292700001
资助机构We extend our gratitude to Yongping Zhao, Shu Yang, Ying Gao, Siying Kong, and Xiaoxiao Sun from the Tianjin Anding Hospital for their assistance in data collection.
源URL[http://ir.psych.ac.cn/handle/311026/46246]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Zhang, Xiangyang; Li, Jie
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, 16 Lincui Rd, Beijing 100101, Peoples R China
2.Tianjin Med Univ, Tianjin Anding Hosp, Inst Mental Hlth, Lab Biol Psychiat,Mental Hlth Ctr, 13 Liulin Rd, Tianjin 300222, Peoples R China
推荐引用方式
GB/T 7714		 Luo, Guoshuai,Li, Meijuan,Qiu, Yuying,et al. Gender differences and clinical correlates in the age of the first hospitalization in patients with drug-na&iuml;ve schizophrenia in China: a cross-sectional study[J]. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE,2023:10.
APA Luo, Guoshuai,Li, Meijuan,Qiu, Yuying,Yao, Cong,Zhang, Xiangyang,&Li, Jie.(2023).Gender differences and clinical correlates in the age of the first hospitalization in patients with drug-naïve schizophrenia in China: a cross-sectional study.EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE,10.
MLA Luo, Guoshuai,et al."Gender differences and clinical correlates in the age of the first hospitalization in patients with drug-naïve schizophrenia in China: a cross-sectional study".EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2023):10.

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来源：心理研究所

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