Heterogeneous asymmetric β-C-H functionalization of aldehydes under O2 catalyzed by hydroxide-layered Fe(III) sites synergistic with confined interlayer amine
文献类型：期刊论文
| 作者 | An, Zhe; Han, Hongbo; Zhong, Jianning; Zhang, Jian ; Zhu, Yanru; Shu, Xin; Song, Hongyan; Wang, Wenlong; Zheng, Lirong; Qing, Ming
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| 刊名 | Journal of Catalysis
 |
| 出版日期 | 2022 |
| 卷号 | 414页码:267-276 |
| ISSN号 | 00219517 |
| DOI | 10.1016/j.jcat.2022.09.009 |
| 文献子类 | Article |
| 英文摘要 | Asymmetric functionalization of inert β-C-H is one of the most powerful strategies in organic synthesis, but of great challenge in the efficient β-C-H activation and the enantioselective C-heteroatom formation. Here, this work proposes an elegant strategy for one-pot asymmetric β-C-H functionalization of aldehyde under O2 catalyzed by hydroxide-layered Fe(III) sites synergistic with confined interlayer amine through a cascade oxidation-addition process on L-proline intercalated Fe-containing layered double hydroxides (LDHs), in which the direct β-H elimination of aldehyde on hydroxide-layered Fe(III) sites with the two-electron abstraction promoted by the Fe(III):N coordination as the key step to efficiently oxidize the enamine. The major β-functionalized diastereomer in the asymmetric nitromethylation of 3-phenylpropanal has been afforded in a regioselectivity of up to >99%, a stereoselectivity of 90%, and a yield of 65% on L-proline intercalated Mg3.00Al0.47Fe0.45-LDHs. © 2022 Elsevier Inc. |
| 电子版国际标准刊号 | 10902694 |
| 语种 | 英语 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/299605]  |
| 专题 | 高能物理研究所_实验物理中心 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | An, Zhe,Han, Hongbo,Zhong, Jianning,et al. Heterogeneous asymmetric β-C-H functionalization of aldehydes under O2 catalyzed by hydroxide-layered Fe(III) sites synergistic with confined interlayer amine[J]. Journal of Catalysis,2022,414:267-276. |
| APA | An, Zhe.,Han, Hongbo.,Zhong, Jianning.,Zhang, Jian.,Zhu, Yanru.,...&He, Jing.(2022).Heterogeneous asymmetric β-C-H functionalization of aldehydes under O2 catalyzed by hydroxide-layered Fe(III) sites synergistic with confined interlayer amine.Journal of Catalysis,414,267-276. |
| MLA | An, Zhe,et al."Heterogeneous asymmetric β-C-H functionalization of aldehydes under O2 catalyzed by hydroxide-layered Fe(III) sites synergistic with confined interlayer amine".Journal of Catalysis 414(2022):267-276. |
入库方式： OAI收割
来源：高能物理研究所
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