Preparation and characterization of large porous poly(HEMA-co-EDMA) microspheres with narrow size distribution by modified membrane emulsification method
文献类型：期刊论文
| 作者 | Qu, Huanhuan; Gong, Fangling; Ma, Guanghui; Su, Zhiguo |
| 刊名 | JOURNAL OF APPLIED POLYMER SCIENCE
 |
| 出版日期 | 2007-08-05 |
| 卷号 | 105期号:3页码:1632-1641 |
| 关键词 | HEMA membrane emulsification particle size distribution phase separation swelling |
| ISSN号 | 0021-8995 |
| 其他题名 | J. Appl. Polym. Sci. |
| 中文摘要 | Porous poly(2-hydroxyethyl methacrylate-coethylene chmethacrylate) [p(HENIA-co-EDNIA)] microspheres have important applications in chromatography. In this study, p(HENIA-co-EDNIA) microspheres with controllable size were successfully prepared by modified membrane emulsification technique. The CV value of the obtained n-Licrospheres was as low as 14.4%. An oil phase mainly composed of toluene was permeated through a membrane with uniform pores into an aqueous phase to form fairly uniform seed emulsion. The secondary emulsion composed of HEMA and EDMA was prepared by a homogenizer. Then, the two emulsions were mixed together. HEMA and EDMA diffused into the aqueous phase, and then were absorbed by the seed droplets. The swollen droplets were further polymerized to prepare monodisperse porous microspheres. It was found that HEMA/EDMA ratio and toluene/monomer ratio showed a significant influence on swelling degree, diameter, and morphology of the obtained microspheres. The swelling degree of the microspheres increased with the increase of toluene/monomer ratio, whereas the average diameter increased with decrease of the ratio. Microspheres with controllable size (28-73 mu m) and porosity were obtained, by varying HEMA/EDMA ratios and toluene/monomer ratios. It can be expected that the p(HEMA-co-EDMA) microspheres with controllable size and porosity will provide many advantages in their applications. (c) 2007 Wiley Periodicals, Inc. |
| 英文摘要 | Porous poly(2-hydroxyethyl methacrylate-coethylene chmethacrylate) [p(HENIA-co-EDNIA)] microspheres have important applications in chromatography. In this study, p(HENIA-co-EDNIA) microspheres with controllable size were successfully prepared by modified membrane emulsification technique. The CV value of the obtained n-Licrospheres was as low as 14.4%. An oil phase mainly composed of toluene was permeated through a membrane with uniform pores into an aqueous phase to form fairly uniform seed emulsion. The secondary emulsion composed of HEMA and EDMA was prepared by a homogenizer. Then, the two emulsions were mixed together. HEMA and EDMA diffused into the aqueous phase, and then were absorbed by the seed droplets. The swollen droplets were further polymerized to prepare monodisperse porous microspheres. It was found that HEMA/EDMA ratio and toluene/monomer ratio showed a significant influence on swelling degree, diameter, and morphology of the obtained microspheres. The swelling degree of the microspheres increased with the increase of toluene/monomer ratio, whereas the average diameter increased with decrease of the ratio. Microspheres with controllable size (28-73 mu m) and porosity were obtained, by varying HEMA/EDMA ratios and toluene/monomer ratios. It can be expected that the p(HEMA-co-EDMA) microspheres with controllable size and porosity will provide many advantages in their applications. (c) 2007 Wiley Periodicals, Inc. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Polymer Science |
| 研究领域[WOS] | Polymer Science |
| 关键词[WOS] | MONODISPERSE POLYMER PARTICLES ; GLASS EMULSIFICATION ; 2-HYDROXYETHYL METHACRYLATE ; CHROMATOGRAPHY ; DROPLETS |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000247576000075 |
| 公开日期 | 2013-10-15 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/3421]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100080, Peoples R China 2.Grad Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qu, Huanhuan,Gong, Fangling,Ma, Guanghui,et al. Preparation and characterization of large porous poly(HEMA-co-EDMA) microspheres with narrow size distribution by modified membrane emulsification method[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2007,105(3):1632-1641. |
| APA | Qu, Huanhuan,Gong, Fangling,Ma, Guanghui,&Su, Zhiguo.(2007).Preparation and characterization of large porous poly(HEMA-co-EDMA) microspheres with narrow size distribution by modified membrane emulsification method.JOURNAL OF APPLIED POLYMER SCIENCE,105(3),1632-1641. |
| MLA | Qu, Huanhuan,et al."Preparation and characterization of large porous poly(HEMA-co-EDMA) microspheres with narrow size distribution by modified membrane emulsification method".JOURNAL OF APPLIED POLYMER SCIENCE 105.3(2007):1632-1641. |
入库方式： OAI收割
来源：过程工程研究所
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