Lipids and Terpenoids from the Deep-Sea Fungus Trichoderma lixii R22 and Their Antagonism against Two Wheat Pathogens
文献类型：期刊论文
| 作者 | Li, Chang-Peng2,3; Shi, Zhen-Zhen3; Fang, Sheng-Tao3 ; Song, Yin-Ping3; Ji, Nai-Yun1,2,3
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| 刊名 | MOLECULES
 |
| 出版日期 | 2023-09-01 |
| 卷号 | 28期号:17页码:10 |
| 关键词 | Trichoderma lipid terpenoid butenolide brasilane fungicide |
| DOI | 10.3390/molecules28176220 |
| 通讯作者 | Ji, Nai-Yun(nyji@yic.ac.cn) |
| 英文摘要 | Five new lipids, tricholixins A-E (1-5), and two known terpenoids, brasilane A (6) and harzianone A (7), were discovered from a deep-sea strain (R22) of the fungus Trichoderma lixii isolated from the cold seep sediments of the South China Sea. Their structures and relative configurations were identified by meticulous analysis of MS and IR as well as NMR data. The absolute configuration of 5 was ascertained by dimolybdenum-induced ECD data in particular. Compounds 1 and 2 represent the only two new butenolides from marine-derived Trichoderma, and they further add to the structural diversity of these molecules. Although 6 has been reported from a basidiomycete previously, it is the first brasilane aminoglycoside of Trichoderma origin. During the assay against wheat-pathogenic fungi, both 1 and 2 inhibited Fusarium graminearum with an MIC value of 25.0 mu g/mL, and 6 suppressed Gaeumannomyces graminis with an MIC value of 12.5 mu g/mL. Moreover, the three isolates also showed low toxicity to the brine shrimp Artemia salina. |
| WOS关键词 | SECONDARY METABOLITES ; DERIVATIVES ; ANTIBIOTICS ; ANTIFUNGAL ; CULTURES ; STRAINS ; ALGA |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001070077900001 |
| 资助机构 | The authors acknowledgment Xiu-Li Yin and Ke Li (Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences) for their technical support of NMR and HRESIMS. ; Yantai Institute of Coastal Zone Research |
| 源URL | [http://ir.yic.ac.cn/handle/133337/32878]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Ji, Nai-Yun |
| 作者单位 | 1.Shandong Saline Alkaline Land Modern Agr Co, Dongying 257345, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Chang-Peng,Shi, Zhen-Zhen,Fang, Sheng-Tao,et al. Lipids and Terpenoids from the Deep-Sea Fungus Trichoderma lixii R22 and Their Antagonism against Two Wheat Pathogens[J]. MOLECULES,2023,28(17):10. |
| APA | Li, Chang-Peng,Shi, Zhen-Zhen,Fang, Sheng-Tao,Song, Yin-Ping,&Ji, Nai-Yun.(2023).Lipids and Terpenoids from the Deep-Sea Fungus Trichoderma lixii R22 and Their Antagonism against Two Wheat Pathogens.MOLECULES,28(17),10. |
| MLA | Li, Chang-Peng,et al."Lipids and Terpenoids from the Deep-Sea Fungus Trichoderma lixii R22 and Their Antagonism against Two Wheat Pathogens".MOLECULES 28.17(2023):10. |
入库方式： OAI收割
来源：烟台海岸带研究所
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