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Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer

文献类型：期刊论文

作者Zhang, Haoran5,6; Zhang, Bo5,6; Feng, Xin1,4; Zhang, Yingqian2,3; Chen, Yundai2,3; Hui, Hui1,4; Tian, Jie5,6
刊名IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
出版日期2023
卷号72页码:10
关键词Arbitrary frequency magnetic nanoparticles (MNPs) magnetic particle spectrometer (MPS) viscosity measurement
ISSN号0018-9456
DOI10.1109/TIM.2023.3298428
通讯作者Hui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org)
英文摘要Magnetic particle spectrometer (MPS) is the device for characterizing the properties of magnetic nanoparticle (MNP) suspensions, such as viscosity, temperature, and concentration. Specifically, in viscosity measurement, MPS usually works at one or several fixed frequencies. It is challenging to find the appropriate frequency for viscosity measurement of different MNP suspensions. The frequency parameter can be introduced into the measurement method to improve the measurement accuracy. Here, we developed an arbitrary frequency MPS to measure the harmonic amplitudes of the magnetization signals of MNPs, which were generated at various frequencies. A method of measuring the viscosity of MNP suspensions by harmonic ratios at different frequencies was proposed. The viscosity measurement time used in the experiment is 1 s, and the shortest measurement time available is 0.2 s. Experimental results show that the arbitrary frequency MPS can measure the viscosity of samples ranging from 0.77 mPa.s to 3.87 mPa.s, and the average measurement deviation is 2.7%. The method was validated using plasma samples from normal rabbits and high-fat diet (HFD) rabbits. Normal rabbit measurements differed from the reference by less than 4.5%, and the plasma viscosity of normal and HFD rabbits could be clearly distinguished.
WOS关键词WHOLE-BLOOD VISCOSITY ; PLASMA
资助项目National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81227901] ; Beijing Natural Science Foundation[JQ22023] ; Beijing Natural Science Foundation[7232346] ; Chinese Academy of Sciences Youth Innovation Promotion Association[Y2022055] ; Key Technology Talent Program
WOS研究方向Engineering ; Instruments & Instrumentation
语种英语
WOS记录号WOS:001045579100022
出版者IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; Beijing Natural Science Foundation ; Chinese Academy of Sciences Youth Innovation Promotion Association ; Key Technology Talent Program
源URL[http://ir.ia.ac.cn/handle/173211/54062]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Hui, Hui; Tian, Jie
作者单位1.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China
2.Sixth Med Ctr PLA Gen Hosp, Beijing 100048, Peoples R China
3.Sr Dept Cardiol, Beijing 100048, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100190, Peoples R China
5.Beihang Univ, Key Lab Big DataBased Precis Med, Minist Ind & Informat Technol China, Beijing 100191, Peoples R China
6.Beihang Univ, Sch Engn Med, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Haoran,Zhang, Bo,Feng, Xin,et al. Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2023,72:10.
APA Zhang, Haoran.,Zhang, Bo.,Feng, Xin.,Zhang, Yingqian.,Chen, Yundai.,...&Tian, Jie.(2023).Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,72,10.
MLA Zhang, Haoran,et al."Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 72(2023):10.

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来源：自动化研究所

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