Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing
文献类型：期刊论文
| 作者 | Xie, Xianghong; Lei, Yulu; Li, Ying; Zhang, Mingyu; Sun, Jing; Zhu, Ming-Qiang; Wang, Jianlong |
| 刊名 | JOURNAL OF COLLOID AND INTERFACE SCIENCE
 |
| 出版日期 | 2023 |
| 卷号 | 637页码:20 |
| 英文摘要 | Adhesive hydrogels have emerged as promising candidates to solve life-threatening infectious skin inju-ries. However, the inadequate mechanical characteristics and biological adherence limit the traditional wound dressing unable to adapt to high-frequency movement and real-time monitoring of wound heal-ing, calling for the development of bioadhesive materials guided wound healing. In this work, a multi-functional bioadhesive hydrogel with double colorimetric-integrated of polyethylene glycol (PVA)-dextran (Dex)-borax-bromothymol blue (BTB)-fluorescein thiocyanate (FITC) and functionalization by tungsten disulfide-catechol nanozyme (CL/WS2) was created. Hydrogel is a perfect biological adhesive, which can achieve repeatable and strong tissue adhesion strength (8.3 +/- 0.6 kPa), which is 1.66 times that of commercial dressings. Based on the strong biological adhesion of the hydrogel, a sensor is integrated into the hydrogel to collect visual image of bacterial infection from a smartphone and transform it into an on-site pH signal for remote evaluation of the wound's dynamic status in real time. Ultimately, the adhe-siveness hydrogel has high worth in managing the burden related to wound healing and paving the way for intelligent wound management in the future.(c) 2023 Published by Elsevier Inc. |
| 源URL | [http://210.75.249.4/handle/363003/61709]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Xie, Xianghong,Lei, Yulu,Li, Ying,et al. Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2023,637:20. |
| APA | Xie, Xianghong.,Lei, Yulu.,Li, Ying.,Zhang, Mingyu.,Sun, Jing.,...&Wang, Jianlong.(2023).Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing.JOURNAL OF COLLOID AND INTERFACE SCIENCE,637,20. |
| MLA | Xie, Xianghong,et al."Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing".JOURNAL OF COLLOID AND INTERFACE SCIENCE 637(2023):20. |
入库方式： OAI收割
来源：西北高原生物研究所
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