中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Inferring functional connectivity in fmri using minimum partial correlation

文献类型:期刊论文

作者Nie Lei1; Yang Xian1; Matthews Paul M1; Xu Zhiwei2; Guo Yike1
刊名International journal of automation and computing
出版日期2017
卷号14期号:4页码:371
关键词Functional connectivity Functional magnetic resonance imaging (fmri) Network modelling Partial correlation Pc-algorithm Resting-state networks
ISSN号1476-8186
英文摘要Functional connectivity has emerged as a promising approach to study the functional organisation of the brain and to define features for prediction of brain state. The most widely used method for inferring functional connectivity is Pearson's correlation, but it cannot differentiate direct and indirect effects. This disadvantage is often avoided by computing the partial correlation between two regions controlling all other regions, but this method suffers from Berkson's paradox. Some advanced methods, such as regularised inverse covariance, have been applied. However, these methods usually depend on some parameters. Here we propose use of minimum partial correlation as a parameter-free measure for the skeleton of functional connectivity in functional magnetic resonance imaging(fMRI). The minimum partial correlation between two regions is the minimum of absolute values of partial correlations by controlling all possible subsets of other regions. Theoretically, there is a direct effect between two regions if and only if their minimum partial correlation is non-zero under faithfulness and Gaussian assumptions. The elastic PC-algorithm is designed to efficiently approximate minimum partial correlation within a computational time budget. The simulation study shows that the proposed method outperforms others in most cases and its application is illustrated using a resting-state fMRI dataset from the human connectome project.
语种英语
源URL[http://119.78.100.204/handle/2XEOYT63/35107]  
专题中国科学院计算技术研究所期刊论文_中文
作者单位1.伦敦帝国学院
2.中国科学院计算技术研究所
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GB/T 7714
Nie Lei,Yang Xian,Matthews Paul M,et al. Inferring functional connectivity in fmri using minimum partial correlation[J]. International journal of automation and computing,2017,14(4):371.
APA Nie Lei,Yang Xian,Matthews Paul M,Xu Zhiwei,&Guo Yike.(2017).Inferring functional connectivity in fmri using minimum partial correlation.International journal of automation and computing,14(4),371.
MLA Nie Lei,et al."Inferring functional connectivity in fmri using minimum partial correlation".International journal of automation and computing 14.4(2017):371.

入库方式: OAI收割

来源:计算技术研究所

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