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Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder

文献类型：期刊论文

作者Zhang, Jian-Jun5,6; Wang, Xiao-Qian6; Zeng, Qun4; Gao, Na2,3; Zhang, Xiang-Yang1,5
刊名FRONTIERS IN PSYCHIATRY
出版日期2023-10-18
卷号14页码:8
关键词overweight obesity major depressive disorder (MDD) young first episode and drug naive (FEDN) patients
ISSN号1664-0640
DOI10.3389/fpsyt.2023.1278566
通讯作者Zhang, Xiang-Yang(zhangxy@psych.ac.cn)
英文摘要BackgroundObesity and overweight are common in young patients with major depressive disorder (MDD). However, the prevalence and associated clinical factors of obesity/overweight in young first-episode and drug-naive (FEDN) MDD patients are rarely reported in China.MethodsA cross-sectional study of 917 young patients (aged 18-35 years) with FEDN MDD was performed. Demographic and clinical data were collected. Depression, anxiety, and psychotic symptoms were assessed using the Hamilton Depression Scale (HAMD), the Hamilton Anxiety Scale (HAMA), and the Positive and Negative Syndrome Scale (PANSS) positive subscale, respectively.ResultsAmong the young MDD patients, the prevalence of obesity and overweight was 4.14 and 52.89%, respectively. Compared to normal-weight patients, overweight patients were older, had a greater age of onset, and had higher TSH and TG levels. Male MDD patients had a higher risk of obesity than female patients. Compared to obese patients, normal-weight and overweight patients had significantly lower HAMD scores, TC levels, and rates of TSH abnormalities. Logistic regression analysis showed that age, age of onset, and sex were independently associated with obesity, and TSH was independently associated with both obesity and overweight, in young MDD patients.ConclusionOur findings suggest a high prevalence of overweight and obesity in young FEDN MDD patients. Several demographic and clinical variables are independently associated with overweight/obesity in these young MDD patients.
收录类别SCI
WOS关键词BODY-MASS INDEX ; RISK-FACTORS ; WAIST CIRCUMFERENCE ; METABOLIC SYNDROME ; ADULTS ; OUTPATIENTS ; EPISODE ; GENDER ; ONSET
资助项目The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Chinese National Programs for Brain Science and Brain-like Intelligence Technology (2021ZD0202102), the Na[2021ZD0202102] ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology[31871111] ; National Natural Science Foundation of China[2020088] ; Youth Innovation Promotion Association CAS
WOS研究方向Psychiatry
语种英语
WOS记录号WOS:001090785500001
出版者FRONTIERS MEDIA SA
资助机构The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Chinese National Programs for Brain Science and Brain-like Intelligence Technology (2021ZD0202102), the Na ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology ; National Natural Science Foundation of China ; Youth Innovation Promotion Association CAS
源URL[http://ir.psych.ac.cn/handle/311026/46332]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Zhang, Xiang-Yang
作者单位1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
2.Chinese Peoples Liberat Army PLA Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Beijing, Peoples R China
3.Chinese Peoples Liberat Army PLA Gen Hosp, Dept Cardiol, Med Ctr 2, Beijing, Peoples R China
4.Shanxi Univ Chinese Med, Coll Basic Med Sci, Jinzhong, Peoples R China
5.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
6.Shanxi Univ Chinese Med, Natl Int Joint Res Ctr Mol Chinese Med, Shanxi Key Lab Chinese Med Encephalopathy, Taiyuan, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Jian-Jun,Wang, Xiao-Qian,Zeng, Qun,et al. Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder[J]. FRONTIERS IN PSYCHIATRY,2023,14:8.
APA Zhang, Jian-Jun,Wang, Xiao-Qian,Zeng, Qun,Gao, Na,&Zhang, Xiang-Yang.(2023).Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder.FRONTIERS IN PSYCHIATRY,14,8.
MLA Zhang, Jian-Jun,et al."Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder".FRONTIERS IN PSYCHIATRY 14(2023):8.

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来源：心理研究所

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