Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder
文献类型:期刊论文
作者 | Zhang, Jian-Jun5,6![]() ![]() |
刊名 | FRONTIERS IN PSYCHIATRY
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出版日期 | 2023-10-18 |
卷号 | 14页码:8 |
关键词 | overweight obesity major depressive disorder (MDD) young first episode and drug naive (FEDN) patients |
ISSN号 | 1664-0640 |
DOI | 10.3389/fpsyt.2023.1278566 |
通讯作者 | Zhang, Xiang-Yang(zhangxy@psych.ac.cn) |
英文摘要 | BackgroundObesity and overweight are common in young patients with major depressive disorder (MDD). However, the prevalence and associated clinical factors of obesity/overweight in young first-episode and drug-naive (FEDN) MDD patients are rarely reported in China.MethodsA cross-sectional study of 917 young patients (aged 18-35 years) with FEDN MDD was performed. Demographic and clinical data were collected. Depression, anxiety, and psychotic symptoms were assessed using the Hamilton Depression Scale (HAMD), the Hamilton Anxiety Scale (HAMA), and the Positive and Negative Syndrome Scale (PANSS) positive subscale, respectively.ResultsAmong the young MDD patients, the prevalence of obesity and overweight was 4.14 and 52.89%, respectively. Compared to normal-weight patients, overweight patients were older, had a greater age of onset, and had higher TSH and TG levels. Male MDD patients had a higher risk of obesity than female patients. Compared to obese patients, normal-weight and overweight patients had significantly lower HAMD scores, TC levels, and rates of TSH abnormalities. Logistic regression analysis showed that age, age of onset, and sex were independently associated with obesity, and TSH was independently associated with both obesity and overweight, in young MDD patients.ConclusionOur findings suggest a high prevalence of overweight and obesity in young FEDN MDD patients. Several demographic and clinical variables are independently associated with overweight/obesity in these young MDD patients. |
收录类别 | SCI |
WOS关键词 | BODY-MASS INDEX ; RISK-FACTORS ; WAIST CIRCUMFERENCE ; METABOLIC SYNDROME ; ADULTS ; OUTPATIENTS ; EPISODE ; GENDER ; ONSET |
资助项目 | The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Chinese National Programs for Brain Science and Brain-like Intelligence Technology (2021ZD0202102), the Na[2021ZD0202102] ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology[31871111] ; National Natural Science Foundation of China[2020088] ; Youth Innovation Promotion Association CAS |
WOS研究方向 | Psychiatry |
语种 | 英语 |
WOS记录号 | WOS:001090785500001 |
出版者 | FRONTIERS MEDIA SA |
资助机构 | The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Chinese National Programs for Brain Science and Brain-like Intelligence Technology (2021ZD0202102), the Na ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology ; National Natural Science Foundation of China ; Youth Innovation Promotion Association CAS |
源URL | [http://ir.psych.ac.cn/handle/311026/46332] ![]() |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Zhang, Xiang-Yang |
作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 2.Chinese Peoples Liberat Army PLA Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Beijing, Peoples R China 3.Chinese Peoples Liberat Army PLA Gen Hosp, Dept Cardiol, Med Ctr 2, Beijing, Peoples R China 4.Shanxi Univ Chinese Med, Coll Basic Med Sci, Jinzhong, Peoples R China 5.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 6.Shanxi Univ Chinese Med, Natl Int Joint Res Ctr Mol Chinese Med, Shanxi Key Lab Chinese Med Encephalopathy, Taiyuan, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Jian-Jun,Wang, Xiao-Qian,Zeng, Qun,et al. Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder[J]. FRONTIERS IN PSYCHIATRY,2023,14:8. |
APA | Zhang, Jian-Jun,Wang, Xiao-Qian,Zeng, Qun,Gao, Na,&Zhang, Xiang-Yang.(2023).Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder.FRONTIERS IN PSYCHIATRY,14,8. |
MLA | Zhang, Jian-Jun,et al."Prevalence and associated clinical factors for overweight and obesity in young first-episode and drug-naïve Chinese patients with major depressive disorder".FRONTIERS IN PSYCHIATRY 14(2023):8. |
入库方式: OAI收割
来源:心理研究所
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