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Morphological characteristics of beak-like tooth in spotted knifejaw (Oplegnathus punctatus) and mechanisms of dental development regulation by the Wnt, BMP, FGF and SHH signalling pathways

文献类型：期刊论文

作者Ma, Yuting; Xiao, Yongshuang1,2; Xiao, Zhizhong; Li, Jun1,2
刊名INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
出版日期2023-10-01
卷号250页码:19
关键词Oplegnathus punctatus Beak-like tooth Tooth development Mesenchymal cells BMP Vitamin D metabolism
ISSN号0141-8130
DOI10.1016/j.ijbiomac.2023.126188
通讯作者Xiao, Yongshuang(yongshuangxiao@qdio.ac.cn) ; Li, Jun(yongshuangxiao@qdio.ac.cn)
英文摘要Oplegnathus punctatus is a fish species with beak-like tooth that feeds on algae, oysters, sea urchins, and other organisms attached to rocks. Currently, there are no research reports on the development and regulatory mechanisms of O. punctatus beak-like tooth. This present study firstly elucidated the nesting structure pattern of the beak-like tooth with dental formula (4, 15-16, 10-1) for O. punctatus. Four critical periods during early beak-like tooth development (28dph, 40dph, 50dph, 60dph) were also identified. In addition, 11 key genes (bmp2, bmpr2, smad1, wnt5a, msx, axin2, fgfr1a, fgfr2, pitx2, ptch1, cyp27a1) closely related to the development of beak-like tooth were discovered, with the highest expression levels in the initial stages of functional teeth and replacement teeth development, and expression in the mesenchymal and epithelial tissues of the teeth. Further research found that the cyp27a1 gene, related to vitamin D metabolism and calcium accumulation, was expressed in the maxilla and base of the tooth in O. punctatus. This study provides support for the biological theory of tooth development and healing and provides a reference for the adaptive evolution of tooth healing in special habitats.
WOS关键词TEETH ; EXPRESSION ; REGENERATION ; PERCIFORMES ; PUFFERFISH ; STRINGTIE ; KNOWLEDGE ; SCARIDAE ; TELEOST ; FISHES
资助项目National Natural Science Foundation of China[42276107] ; National Key Research and Development Program[2022YFC3103600] ; Key Deployment Projects of Center for Ocean Mega-Science, Chinese Academy of Sciences[CARS-47] ; CARs for Marine Fish Culture Industry ; [COMS2020Q05]
WOS研究方向Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
语种英语
WOS记录号WOS:001088418700001
出版者ELSEVIER
源URL[http://ir.qdio.ac.cn/handle/337002/181604]  
专题海洋研究所_实验海洋生物学重点实验室
通讯作者Xiao, Yongshuang; Li, Jun
作者单位1.Chinese Acad Sci, Qingdao, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China
4.Chinese Acad Sci, Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan, Peoples R China
推荐引用方式
GB/T 7714		 Ma, Yuting,Xiao, Yongshuang,Xiao, Zhizhong,et al. Morphological characteristics of beak-like tooth in spotted knifejaw (Oplegnathus punctatus) and mechanisms of dental development regulation by the Wnt, BMP, FGF and SHH signalling pathways[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2023,250:19.
APA Ma, Yuting,Xiao, Yongshuang,Xiao, Zhizhong,&Li, Jun.(2023).Morphological characteristics of beak-like tooth in spotted knifejaw (Oplegnathus punctatus) and mechanisms of dental development regulation by the Wnt, BMP, FGF and SHH signalling pathways.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,250,19.
MLA Ma, Yuting,et al."Morphological characteristics of beak-like tooth in spotted knifejaw (Oplegnathus punctatus) and mechanisms of dental development regulation by the Wnt, BMP, FGF and SHH signalling pathways".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 250(2023):19.

入库方式： OAI收割

来源：海洋研究所

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