Metabolic and oxidative stress response of sea cucumber Apostichopus japonicus exposed to acute high concentration of bisphenol AF
文献类型：期刊论文
| 作者 | Lai, Kaiqi1,2,3; Zhang, Libin1,2,3; Xu, Jialei4 |
| 刊名 | AQUATIC TOXICOLOGY
 |
| 出版日期 | 2023-09-01 |
| 卷号 | 262页码:9 |
| ISSN号 | 0166-445X |
| 关键词 | Endocrine disruptor Bisphenol AF Sea cucumber Metabolic response Oxidative stress response |
| DOI | 10.1016/j.aquatox.2023.106654 |
| 通讯作者 | Zhang, Libin(zhanglibin@qdio.ac.cn) |
| 英文摘要 | Bisphenols are known as endocrine disruptor that affect the development, and growth of marine creatures, including human. There were plenty of manuscripts evaluated the toxicology of bisphenol A (BPA) and its analogues such as bisphenol F (BPF), bisphenol AF (BPAF), and bisphenol S (BPS), but limits of them studied the effects of bisphenol analogues on echinoderms. In this study, we used metabolomics to investigate the metabolic response of sea cucumber (Apostichopus japonicus) exposed to BPAF, and the activities of glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD) were determined. The results demonstrated alterations in lipid metabolism, glycerophospholipid metabolism, and biosynthesis of amino acids following BPAF treatment. Sea cucumbers upregulated the glycerophospholipid metabolism to repair the destruction of intestine cellular homeostasis. Six metabolites were selected as the potential biomarkers for the exposure of BPAF. This study revealed the metabolic response and oxidative response of sea cucumber arising from BPAF exposure, and provided theoretical support for the risk assessment of bisphenol analogues on economically important echinoderms, such as A. japonicus. |
| WOS关键词 | ACUTE TOXICITY ; ANALOGS ; HEALTH |
| 资助项目 | National Natural Science Foundation of China[42061160365] |
| WOS研究方向 | Marine & Freshwater Biology ; Toxicology |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:001062311900001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/181850]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Zhang, Libin |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Tonghe Shandong Ocean Technol Co Ltd, Dongying 257200, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lai, Kaiqi,Zhang, Libin,Xu, Jialei. Metabolic and oxidative stress response of sea cucumber Apostichopus japonicus exposed to acute high concentration of bisphenol AF[J]. AQUATIC TOXICOLOGY,2023,262:9. |
| APA | Lai, Kaiqi,Zhang, Libin,&Xu, Jialei.(2023).Metabolic and oxidative stress response of sea cucumber Apostichopus japonicus exposed to acute high concentration of bisphenol AF.AQUATIC TOXICOLOGY,262,9. |
| MLA | Lai, Kaiqi,et al."Metabolic and oxidative stress response of sea cucumber Apostichopus japonicus exposed to acute high concentration of bisphenol AF".AQUATIC TOXICOLOGY 262(2023):9. |
入库方式： OAI收割
来源：海洋研究所
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