The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement
文献类型：期刊论文
| 作者 | Tian, Luqi4,5,6; Xing, Ronge1,2,3,5,6 ; Yang, Haoyue5,6; Liu, Song3,5,6; Yu, Huahua3,5,6; Li, Pengcheng3,5,6
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| 刊名 | INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
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| 出版日期 | 2023-08-05 |
| 页码 | 10 |
| ISSN号 | 0091-4037 |
| 关键词 | Conch shell HACC hydroxyapatite PMMA bone cement > |
| DOI | 10.1080/00914037.2023.2243367 |
| 通讯作者 | Xing, Ronge(xingronge@qdio.ac.cn) |
| 英文摘要 | In this study, we acquired conch-shell Hydroxyapatite (cHA)with a mean size of 99.41 nm using a microwave-assisted method, and hydroxypropyl trimethyl ammonium chloride chitosan (HACC) with a molecular weight of 41 kDa was synthesized from deacetylated chitosan. These two additives were added to plain PMMA bone cement, improving its biological activity. It was shown that the addition of cHA and HACC balanced the mechanical performance and porosity of the implant, improving its biocompatibility with mouse pre-osteoblasts (MC3T3-E1). A composite cement with 30 wt% cHA and 0.5 wt% HACC significantly enhanced mineralization efficiency, protein adsorption, and alkaline phosphatase (ALP) activity. |
| WOS关键词 | SCAFFOLDS ; BIOACTIVITY |
| 资助项目 | Fujian science and technology planning project-STS program[2021T3013] ; Key deployment projects of the Marine Science Research Center of Chinese Academy of Sciences[COMS2020J04] |
| WOS研究方向 | Materials Science ; Polymer Science |
| 语种 | 英语 |
| 出版者 | TAYLOR & FRANCIS AS |
| WOS记录号 | WOS:001041713200001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/182640]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Xing, Ronge |
| 作者单位 | 1.Chinese Acad Sci, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, Qingdao, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 6.Chinese Acad Sci, Qingdao, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tian, Luqi,Xing, Ronge,Yang, Haoyue,et al. The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement[J]. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,2023:10. |
| APA | Tian, Luqi,Xing, Ronge,Yang, Haoyue,Liu, Song,Yu, Huahua,&Li, Pengcheng.(2023).The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement.INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,10. |
| MLA | Tian, Luqi,et al."The initial application of conch-shell hydroxyapatite and HACC as functional filler in PMMA bone cement".INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2023):10. |
入库方式： OAI收割
来源：海洋研究所
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