Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis
文献类型：期刊论文
| 作者 | Yan, Li-Hong2,3,4; Li, Xin1,2,3 ; Wang, Bin-Gui1,2,3,4
|
| 刊名 | NATURAL PRODUCT REPORTS
 |
| 出版日期 | 2023-08-29 |
| 页码 | 27 |
| ISSN号 | 0265-0568 |
| DOI | 10.1039/d3np00023 |
| 通讯作者 | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 英文摘要 | Covering: up to the end of July, 20231,2-Oxazine is a heterocyclic scaffold rarely found in natural products and is characterized by a directly connected N-O bond in a six-membered ring. Since the discovery of geneserine, the first 1,2-oxazine-containing natural product (1,2-oxazine NP) being isolated from Calabar bean (Physostigma venenosum) in 1925, a total of 76 naturally occurring 1,2-oxazine NPs have been isolated and identified from various sources, which have attracted the attention of researchers in the field of natural product chemistry, organic synthesis, biosynthesis, and pharmacology. This review summarizes the chemical family of 1,2-oxazine NPs, focusing on their source organisms, structural diversities, chemical synthesis, and biosynthesis. This review summarizes the chemical family of natural products with 1,2-oxazine scaffold, focusing on their source organisms, structural diversities, bioactivities, chemical synthesis, and biosynthesis. |
| WOS关键词 | TRICHODERMA CF. BREVICOMPACTUM ; CYTOTOXIC MODIFIED DIPEPTIDES ; INTERSTRAND CROSS-LINKING ; MEK INHIBITOR RO4987655 ; CONCISE TOTAL-SYNTHESIS ; ENDOPHYTIC FUNGUS ; PENICILLIUM-JANTHINELLUM ; HETEROCYCLIC DIPEPTIDES ; ABSOLUTE-CONFIGURATION ; MONOTERPENOID INDOLE |
| 资助项目 | This work was financially supported by the National Natural Science Foundation of China (42076090 and U2006203), by the Shandong Provincial Natural Science Foundation (ZR2021ZD28 and ZR2019ZD18), and by the Senior User Project of RV |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:001055975100001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/182900]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Li-Hong,Li, Xin,Wang, Bin-Gui. Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis[J]. NATURAL PRODUCT REPORTS,2023:27. |
| APA | Yan, Li-Hong,Li, Xin,&Wang, Bin-Gui.(2023).Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis.NATURAL PRODUCT REPORTS,27. |
| MLA | Yan, Li-Hong,et al."Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis".NATURAL PRODUCT REPORTS (2023):27. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。