Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish
文献类型：期刊论文
| 作者 | Wang, Xueqin; Yu, Huahua ; Xing, Ronge; Liu, Song; Chen, Xiaolin; Li, Pengcheng1
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| 刊名 | JOURNAL OF FUNCTIONAL FOODS
 |
| 出版日期 | 2023-06-01 |
| 卷号 | 105页码:12 |
| 关键词 | Monkfish Purification exercise-induced fatigue Immunological effect Transcriptome analysis |
| ISSN号 | 1756-4646 |
| DOI | 10.1016/j.jff.2023.105546 |
| 通讯作者 | Li, Pengcheng(pcli@qdio.ac.cn) |
| 英文摘要 | Monkfish (Lophius litulon) is a nutritious marine product that has attracted increasing attention. In this study, we demonstrated that the monkfish protein hydrolysate (MPH) administration could significantly prolonged the exhaustive swimming time of mice, and increased the hepatic glycogen (HG) level, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxides (GSH-PX) activities; in addition, markedly decreased the blood urea nitrogen (BUN), blood lactic acid (BLA), malonaldehyde (MDA) levels and lactate dehydrogenase (LDH) activity. Furthermore, the MPH administration also enhanced the proliferation of spleen lymphocytes and the activity of natural killer (NK) cells in mice. Besides, 43 peptides from MPH that rich in Phe, His, Ile, Leu and Thr were identified. Finally, 1245 of differentially expressed genes (DEGs) in NC vs MPH-H groups were obtained by transcriptome analysis, and GO classification and enrichment of KEGG pathway were studied. In conclusion, MPH treatment had the anti-fatigue and immunological effects in mice. |
| WOS关键词 | ANTIOXIDANT PEPTIDES ; PROTEIN HYDROLYSATE ; PURIFICATION ; IDENTIFICATION ; EXTRACTS ; ACID ; MICE |
| 资助项目 | Key Projects for Major Projects on the Transformation of Old and Novel Kinetic Energy of Shandong Province[2020-1220] ; STS Project of the Chinese Academy of Sciences[2021T3038] |
| WOS研究方向 | Food Science & Technology ; Nutrition & Dietetics |
| 语种 | 英语 |
| WOS记录号 | WOS:000989717000001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/183135]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Li, Pengcheng |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xueqin,Yu, Huahua,Xing, Ronge,et al. Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish[J]. JOURNAL OF FUNCTIONAL FOODS,2023,105:12. |
| APA | Wang, Xueqin,Yu, Huahua,Xing, Ronge,Liu, Song,Chen, Xiaolin,&Li, Pengcheng.(2023).Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish.JOURNAL OF FUNCTIONAL FOODS,105,12. |
| MLA | Wang, Xueqin,et al."Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish".JOURNAL OF FUNCTIONAL FOODS 105(2023):12. |
入库方式： OAI收割
来源：海洋研究所
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