Increasing production and bio-accessibility of natural astaxanthin in Haematococcus pluvialis by screening and culturing red motile cells under high light condition
文献类型：期刊论文
| 作者 | Chen, Feng2; Xu, Nianjun2; Liu, Kai2 ; Lv, Rongrong2; Shi, Jianxin3; Liu, Jianguo1; Sun, Xue2; Hu, Chaoyang2
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| 刊名 | BIORESOURCE TECHNOLOGY
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| 出版日期 | 2022-11-01 |
| 卷号 | 364页码:8 |
| ISSN号 | 0960-8524 |
| 关键词 | Secondary cell wall Haematococcus pluvialis Transcriptome Wet extraction Simulated gastrointestinal digestion |
| DOI | 10.1016/j.biortech.2022.128067 |
| 通讯作者 | Hu, Chaoyang(huchaoyang@nbu.edu.cn) |
| 英文摘要 | The thick cell wall and low astaxanthin productivity were two important bottlenecks limiting industrial production of astaxanthin via Haematococcus pluvialis. This study reports a strategy for increasing production and bio-accessibility of astaxanthin in H. pluvialis by screening and culturing red motile cells under high light condition. Compared with the original strain NBU489, the biomass of the novel isolated strain RMS10 increased by 31.9% under low light condition, and the astaxanthin content (44.6 mg/g) increased by 53.3% after 9-day high light induction, which were readily extracted and digested without cell disruption. Subsequent transcriptomic analysis confirmed the accumulation of astaxanthin and lipids in RMS10 cells as expression of genes associated with biosynthesis of fatty acid and astaxanthin were up-regulated, while those involved in thick cell wall biosynthesis and reactive oxygen species scavenging were down-regulated in RMS10. Collectively, this study provides a simple and effective method for economical production of natural astaxanthin. |
| WOS关键词 | ACCURATE QUANTIFICATION ; ALGA HAEMATOCOCCUS ; DIRECT EXTRACTION ; ACCUMULATION ; GROWTH ; STRESS |
| 资助项目 | National Key Research and Development Program of China[2018YFD0901500] ; National Key Research and Development Program of China[2018YFD0901506] ; Natural Science Foundation of China[31572638] ; Ningbo Major Project of Science and Technology[2021Z114] |
| WOS研究方向 | Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| WOS记录号 | WOS:000910594400007 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/183299]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Hu, Chaoyang |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Ningbo Univ, Sch Marine Sci, Key Lab Marine Biotechnol Zhejiang Prov, Ningbo 315832, Peoples R China 3.Shanghai Jiao Tong Univ, Yazhou Bay Inst Deepsea Sci Tech, Sch Life Sci & Biotechnol, Joint Int Res Lab Metab Dev Sci, Shanghai 200240, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Feng,Xu, Nianjun,Liu, Kai,et al. Increasing production and bio-accessibility of natural astaxanthin in Haematococcus pluvialis by screening and culturing red motile cells under high light condition[J]. BIORESOURCE TECHNOLOGY,2022,364:8. |
| APA | Chen, Feng.,Xu, Nianjun.,Liu, Kai.,Lv, Rongrong.,Shi, Jianxin.,...&Hu, Chaoyang.(2022).Increasing production and bio-accessibility of natural astaxanthin in Haematococcus pluvialis by screening and culturing red motile cells under high light condition.BIORESOURCE TECHNOLOGY,364,8. |
| MLA | Chen, Feng,et al."Increasing production and bio-accessibility of natural astaxanthin in Haematococcus pluvialis by screening and culturing red motile cells under high light condition".BIORESOURCE TECHNOLOGY 364(2022):8. |
入库方式： OAI收割
来源：海洋研究所
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