Adaptation to hypoxic stress involves amino acid metabolism: A case in sea cucumber
文献类型：期刊论文
| 作者 | Huo, Da1,3,6,7,8; Zhang, Libin1,2,3,6,7,8; Yang, Hongsheng1,2,3,4,6,7,8 ; Sun, Lina1,2,3,4,5,6,7,8
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| 刊名 | ENVIRONMENTAL POLLUTION
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| 出版日期 | 2023-08-01 |
| 卷号 | 330页码:9 |
| ISSN号 | 0269-7491 |
| 关键词 | Hypoxic stress Environmental stress Apostichopus japonicus Metabolome Amino acids |
| DOI | 10.1016/j.envpol.2023.121766 |
| 通讯作者 | Sun, Lina(sunlina@qdio.ac.cn) |
| 英文摘要 | Low dissolved oxygen (LO) in seawater negatively affects aquatic animals , has received considerable attention. However, there is still much to learn about how echinoderms, which are keystone species in benthic ecosystems, respond to hypoxic stress. Here, we detected differentially expressed metabolites (DEMs) in sea cucumber (Apositchopus japonicus) between normoxic conditions (NC group) and hypoxic conditions (2 mg L-1) for 3 and 7 days (i.e., LO3 and LO7 groups). A total of 243, 298 , 178 DEMs were found in the NC versus LO3, NC vs. LO7, and LO3 vs. LO7 comparisons, respectively. Amino acids were the most abundant class of DEMs, and "biosynthesis of amino acids" was an enriched pathway in all three comparisons. Most of the enriched metabolite sets under hypoxic stress were related to metabolism. As the duration of the hypoxia treatment extended, the metabolism-related process maintained an upward trend, and signaling pathways maintained a downward trend. Thus, metabolism-related processes are affected in hypoxia-stressed sea cucumber, and amino acid metabolism is the most important process for adaption to hypoxic conditions, potentially function in osmotic regulation and energy regulation. Our results shed light on the adaptative strategies of sea cucumber to challenging environ-mental conditions. |
| WOS关键词 | APOSTICHOPUS-JAPONICUS ; ALANINE ; OSMOREGULATION ; EXPRESSION ; RESPONSES ; GLYCINE ; INJURY ; ARGININE ; GROWTH ; OXYGEN |
| 资助项目 | National Key R & D Pro- gram of China[2022YFF0802202] ; National Natural Science Foundation of China[42106106] ; National Natural Science Foundation of China[42261160378] ; Key Research and Development Program of Shandong, China[2021LZGC029] ; Shandong Provincial Natural Science Foundation, China[ZR2021QD013] ; Postdoctoral Innovative Talents Support Program of Shandong Province, China[SDBX2020006] ; Special Research Assistant Project of Chinese Academy of Sciences, China |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| WOS记录号 | WOS:001001711000001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/183241]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Sun, Lina |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Innovat Seed Design, Wuhan 430071, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China 6.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 7.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 8.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huo, Da,Zhang, Libin,Yang, Hongsheng,et al. Adaptation to hypoxic stress involves amino acid metabolism: A case in sea cucumber[J]. ENVIRONMENTAL POLLUTION,2023,330:9. |
| APA | Huo, Da,Zhang, Libin,Yang, Hongsheng,&Sun, Lina.(2023).Adaptation to hypoxic stress involves amino acid metabolism: A case in sea cucumber.ENVIRONMENTAL POLLUTION,330,9. |
| MLA | Huo, Da,et al."Adaptation to hypoxic stress involves amino acid metabolism: A case in sea cucumber".ENVIRONMENTAL POLLUTION 330(2023):9. |
入库方式： OAI收割
来源：海洋研究所
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