Third-Generation Sequencing Reveals the Adaptive Role of the Epigenome in Three Deep-Sea Polychaetes
文献类型：期刊论文
| 作者 | Perez, Maeva1,6,7; Aroh, Oluchi5; Sun, Yanan4; Lan, Yi1,6; Juniper, Stanley Kim3; Young, Curtis Robert2; Angers, Bernard7; Qian, Pei-Yuan1,6 |
| 刊名 | MOLECULAR BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2023-08-03 |
| 卷号 | 40期号:8页码:15 |
| 关键词 | epigenomics DNA methylation deep-sea Polychaeta adaptation Nanopore |
| ISSN号 | 0737-4038 |
| DOI | 10.1093/molbev/msad172 |
| 通讯作者 | Perez, Maeva(maeva.perez@umontreal.ca) ; Qian, Pei-Yuan(boqianpy@ust.hk) |
| 英文摘要 | The roles of DNA methylation in invertebrates are poorly characterized, and critical data are missing for the phylum Annelida. We fill this knowledge gap by conducting the first genome-wide survey of DNA methylation in the deep-sea polychaetes dominant in deep-sea vents and seeps: Paraescarpia echinospica, Ridgeia piscesae, and Paralvinella palmiformis. DNA methylation calls were inferred from Oxford Nanopore sequencing after assembling high-quality genomes of these animals. The genomes of these worms encode all the key enzymes of the DNA methylation metabolism and possess a mosaic methylome similar to that of other invertebrates. Transcriptomic data of these polychaetes support the hypotheses that gene body methylation strengthens the expression of housekeeping genes and that promoter methylation acts as a silencing mechanism but not the hypothesis that DNA methylation suppresses the activity of transposable elements. The conserved epigenetic profiles of genes responsible for maintaining homeostasis under extreme hydrostatic pressure suggest DNA methylation plays an important adaptive role in these worms. |
| WOS关键词 | COMPLETE MITOCHONDRIAL GENOME ; DNA CYTOSINE METHYLATION ; CONVERGENT EVOLUTION ; ADAPTATION ; METHIONINE ; INSIGHTS ; TUBEWORM ; METABOLISM ; RETROVIRUS ; GYPSY |
| 资助项目 | Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)[2021HJ01] ; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)[SMSEGL20SC01] ; Major Basic and Applied Research Projects of Guangdong Province[2019B030302004-04] ; GRF ; CRF of HKSAR government[16101822] ; CRF of HKSAR government[C2013-22G] ; Natural Science and Engineering Research Council of Canada[N238600] ; Digital Research Alliance of Canada[4257] ; Natural Science and Engineering Research Council's Alexander Graham Bell fellowship ; Fonds de recherche du Quebec-Nature et Technologie ; Quebec Center |
| WOS研究方向 | Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:001046217200004 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/182780]  |
| 专题 | 海洋研究所_海洋生物分类与系统演化实验室 |
| 通讯作者 | Perez, Maeva; Qian, Pei-Yuan |
| 作者单位 | 1.Southern Marine Sci & Engn Guangdong Lab Guangzhou, Guangzhou, Peoples R China 2.Natl Oceanog Ctr, Southampton, England 3.Univ Victoria, Sch Earth & Ocean Sci, Victoria, BC, Canada 4.Chinese Acad Sci, Inst Oceanol, Lab Marine Organism Taxon & Phylogeny, Qingdao, Peoples R China 5.Auburn Univ, Dept Biol Sci, Auburn, AL USA 6.Hong Kong Univ Sci & Technol, Dept Ocean Sci, Kowloon, Hong Kong, Peoples R China 7.Univ Montreal, Dept Biol Sci, Montreal, PQ, Canada |
| 推荐引用方式 GB/T 7714 | Perez, Maeva,Aroh, Oluchi,Sun, Yanan,et al. Third-Generation Sequencing Reveals the Adaptive Role of the Epigenome in Three Deep-Sea Polychaetes[J]. MOLECULAR BIOLOGY AND EVOLUTION,2023,40(8):15. |
| APA | Perez, Maeva.,Aroh, Oluchi.,Sun, Yanan.,Lan, Yi.,Juniper, Stanley Kim.,...&Qian, Pei-Yuan.(2023).Third-Generation Sequencing Reveals the Adaptive Role of the Epigenome in Three Deep-Sea Polychaetes.MOLECULAR BIOLOGY AND EVOLUTION,40(8),15. |
| MLA | Perez, Maeva,et al."Third-Generation Sequencing Reveals the Adaptive Role of the Epigenome in Three Deep-Sea Polychaetes".MOLECULAR BIOLOGY AND EVOLUTION 40.8(2023):15. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。