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Stretchable Electronic Facial Masks for Skin Electroporation

文献类型：期刊论文

作者Xu XK(徐新凯); Guo L(郭亮); Liu, Hao; Zhou ZX(周赞鑫); Li, Shuang; Gu, Qi; Ding, Shenglong; Guo, Haitao; Yan, Yan; Lan YQ(蓝昱群)
刊名ADVANCED FUNCTIONAL MATERIALS
出版日期2023-11-21
页码14
关键词conductive ink conductive silicone skin electroporation stretchable electronics
ISSN号1616-301X
DOI10.1002/adfm.202311144
通讯作者Su, Yewang(yewangsu@imech.ac.cn)
英文摘要A stretchable electronic facial mask (SEFM) for skin electroporation by transdermal drug delivery is introduced. The SEFM exhibits characteristics of reusability, water-resistant, low cost, and portability. To achieve these objectives while maintaining satisfactory mechanical and electrical performance of the device, two main areas are innovated: (1) Grinding and doping modification of conductive ink to enhance its adhesion to silicone and increase conductivity through material research, as well as mechanical structure design for stretching stability of conductive ink electrodes. (2) Doping modification of high-temperature vulcanizes silicone to address the issue of increased resistance during encapsulation due to the swell of conductive ink. The SEFM designed with these innovations, is validated in rat experiments, demonstrating a 3-4 times increase in drug intake compared to the control group without skin electroporation. Safety is confirmed, and the promotion of niacinamide drug delivery is verified in human volunteers. The materials-modified conductive ink and conductive silicone proposed in SEFM can be employed in other flexible wearable devices, and this platform has the potential for future integration of additional components to achieve expanded functionality and productization. A stretchable electronic facial mask (SEFM) for skin electroporation by transdermal drug delivery, enabling the delivery of drugs such as sodium hyaluronate (SH), aloe powder, beta-glucose, and d-panthenol. The SEFM significantly enhances drug intake, with a 3-4 times increase. This platform holds the potential for future integration of additional components to expand its functionality and facilitate product development.image
分类号一类
WOS关键词HUMAN STRATUM-CORNEUM ; HIGH-VOLTAGE ; TRANSPORT REGIONS ; ULTRASOUND ; MICRONEEDLES ; SILICONE
资助项目Y.S. gratefully acknowledges support from the National Natural Science Foundation of China (grant 12172359), Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (ZDBS-LY-JSC014), and CAS Interdisciplinary Innovation Team (JCTD-2020[12172359] ; National Natural Science Foundation of China[ZDBS-LY-JSC014] ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences[JCTD-2020-03] ; CAS Interdisciplinary Innovation Team
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:001105679100001
资助机构Y.S. gratefully acknowledges support from the National Natural Science Foundation of China (grant 12172359), Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (ZDBS-LY-JSC014), and CAS Interdisciplinary Innovation Team (JCTD-2020 ; National Natural Science Foundation of China ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences ; CAS Interdisciplinary Innovation Team
其他责任者Su, Yewang
源URL[http://dspace.imech.ac.cn/handle/311007/93493]  
专题力学研究所_非线性力学国家重点实验室
力学研究所_高温气体动力学国家重点实验室
力学研究所_流固耦合系统力学重点实验室(2012-)
推荐引用方式
GB/T 7714		 Xu XK,Guo L,Liu, Hao,et al. Stretchable Electronic Facial Masks for Skin Electroporation[J]. ADVANCED FUNCTIONAL MATERIALS,2023:14.
APA 徐新凯.,郭亮.,Liu, Hao.,周赞鑫.,Li, Shuang.,...&苏业旺.(2023).Stretchable Electronic Facial Masks for Skin Electroporation.ADVANCED FUNCTIONAL MATERIALS,14.
MLA 徐新凯,et al."Stretchable Electronic Facial Masks for Skin Electroporation".ADVANCED FUNCTIONAL MATERIALS (2023):14.

入库方式： OAI收割

来源：力学研究所

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