Frontal lobe epilepsy: an eye tracking study of memory and attention
文献类型:期刊论文
作者 | Zhang, Qiong4,5; Sun, Weifeng1,2,3; Huang, Kailing4,5; Qin, Li4,5; Wen, Shirui4,5; Long, Xiaoyan4,5; Wang, Quan2,3; Feng, Li4,5 |
刊名 | FRONTIERS IN NEUROSCIENCE |
出版日期 | 2023-12-05 |
卷号 | 17 |
ISSN号 | 1662-453X |
关键词 | eye tracking memory deficit frontal lobe epilepsy visual attention eye movement |
DOI | 10.3389/fnins.2023.1298468 |
产权排序 | 4 |
英文摘要 | Objective To explore the characteristics and mechanisms of working memory impairment in patients with frontal lobe epilepsy (FLE) through a memory game paradigm combined with eye tracking technology.Method We included 44 patients with FLE and 50 healthy controls (HC). All participants completed a series of neuropsychological scale assessments and a short-term memory game on an automated computer-based memory evaluation platform with an eye tracker.Results Memory scale scores of FLE patients including digit span (U = 747.50, p = 0.007), visual recognition (U = 766.50, p = 0.010), and logical memory (U = 544.00, p < 0.001) were significantly lower than HC. The patients with FLE took longer to complete the four levels of difficulty of the short-term memory game than healthy controls (level 1: U = 2974.50, p = 0.000; level 2: U = 3060.50, p = 0.000; level 3: U = 2465.00, p = 0.000; level 4: U = 2199.00, p = 0.000). During the memory decoding period, first fixation on the targets took significantly longer for FLE patients for all difficulty levels compared to controls (level 1: U = 3407.00, p = 0.008; level 2: U = 3618.00, p = 0.036; level 3: U = 3345.00, p = 0.006; level 4: U = 2781.00, p = 0.000). The average fixation duration per target among patients with FLE was found to be significantly longer compared to HC (level 1: U = 2994.50, p = 0.000; level 2: U = 3101.00, p = 0.000; level 3: U = 2559.50, p = 0.000; level 4: U = 2184.50, p = 0.000). The total fixation duration on AOI/total completion time of FLE patients was significantly lower than those of HC for levels 1 to 3 (level 1: U = 1557.00, p = 0.000; level 2: U = 2333.00, p = 0.000; level 3: U = 2757.00, p = 0.000). Furthermore, the eye tracking data during the memory decoding phase were correlated with neuropsychological scale scores (p < 0.05).Conclusion Patients with FLE exhibited short-term memory impairment probably due to deficits in attentional maintenance, especially during the memory decoding phase. Eye tracking technology provided the possibility to help separate and quantify visual attention from memory processing, contributing to exploring underlying mechanisms of memory impairment in FLE. |
语种 | 英语 |
出版者 | FRONTIERS MEDIA SA |
WOS记录号 | WOS:001127610100001 |
源URL | [http://ir.opt.ac.cn/handle/181661/97096] |
专题 | 西安光学精密机械研究所_光学影像学习与分析中心 |
通讯作者 | Wang, Quan; Feng, Li |
作者单位 | 1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Chinese Acad Sci, Xian Inst Opt & Precis Mech, Key Lab Spectral Imaging Technol, Xian, Peoples R China 3.Chinese Acad Sci, Xian Inst Opt & Precis Mech, Key Lab Biomed Spect Xian, Xian, Peoples R China 4.Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Hunan, Peoples R China 5.Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Qiong,Sun, Weifeng,Huang, Kailing,et al. Frontal lobe epilepsy: an eye tracking study of memory and attention[J]. FRONTIERS IN NEUROSCIENCE,2023,17. |
APA | Zhang, Qiong.,Sun, Weifeng.,Huang, Kailing.,Qin, Li.,Wen, Shirui.,...&Feng, Li.(2023).Frontal lobe epilepsy: an eye tracking study of memory and attention.FRONTIERS IN NEUROSCIENCE,17. |
MLA | Zhang, Qiong,et al."Frontal lobe epilepsy: an eye tracking study of memory and attention".FRONTIERS IN NEUROSCIENCE 17(2023). |
入库方式: OAI收割
来源:西安光学精密机械研究所
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