Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration
文献类型:期刊论文
作者 | Tong, P.4,5; Shi, Y. H.5; Yang, Y.5; Dong, L. P.5; Wu, L. L.5; Sun, T. T.5; Lu, W.3; Zhang, X. Y.1,2 |
刊名 | DEPRESSION AND ANXIETY |
出版日期 | 2023-12-21 |
卷号 | 2023页码:9 |
通讯作者邮箱 | zhangxy@psych.ac.cn (x. y. zhang) |
ISSN号 | 1091-4269 |
DOI | 10.1155/2023/4869276 |
产权排序 | 4 |
文献子类 | 实证研究 |
英文摘要 | Suicidal attempts (SAs) are common in major depressive disorder (MDD). However, only few studies have so far assessed how risk factors for SAs in patients with MDD might be related to the duration of untreated illness (DUI). We interviewed 1,718 drug-naive outpatients with MDD with first-episode SAs and divided them into groups that had and had not attempted suicide. DUI was used as an additional grouping criterion. The patients (20.14%; 346/1718) who had a history of SAs were older and had a longer DUI; lower educational level (middle school-educated only); more psychotic symptoms; higher scores on depression and anxiety scales; and higher BP, plasma BG, TC, and LDL-C levels, but lower HDL-C concentrations. Anxiety symptoms, high education level, and being unmarried were risk factors for SA in patients with MDD with DUIs of <3 months; anxiety symptoms, low BMI, high plasma TC, and low plasma HDL-C were risk factors for SA in the group with DUIs between 3 and 8 months; age, anxiety symptoms, and higher systolic blood pressure were risk factors for those with DUIs>8 months. This study was a single-center cross-sectional survey, and its limitations include a lack of outside validation. Patients with MDD with and without a SA history have different clinical characteristics and metabolic parameters, and risk factors for suicide vary across DUI stages. Anxiety was a general risk factor, suggesting that clinicians should strengthen their assessment of SA risk in patients with MDD during diagnosis and treatment. |
收录类别 | SCI |
WOS关键词 | LATE-LIFE DEPRESSION ; ILLNESS ; OUTCOMES ; ONSET |
资助项目 | Yangzhou University ; Doctoral Start-up Fund of Yangzhou University Affiliated Northern Jiangsu People's Hospital |
WOS研究方向 | Psychology ; Psychiatry |
出版者 | WILEY |
WOS记录号 | WOS:001131928500001 |
资助机构 | Yangzhou University ; Doctoral Start-up Fund of Yangzhou University Affiliated Northern Jiangsu People's Hospital |
源URL | [http://ir.psych.ac.cn/handle/311026/46744] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Zhang, X. Y. |
作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 3.Danyang Peoples Hosp, Dept Neurol, Danyang 212300, Peoples R China 4.Yangzhou Univ, Med Coll, Yangzhou 225001, Peoples R China 5.Northern Jiangsu Peoples Hosp, Dept Clin Psychol, Yangzhou 225001, Peoples R China |
推荐引用方式 GB/T 7714 | Tong, P.,Shi, Y. H.,Yang, Y.,et al. Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration[J]. DEPRESSION AND ANXIETY,2023,2023:9. |
APA | Tong, P..,Shi, Y. H..,Yang, Y..,Dong, L. P..,Wu, L. L..,...&Zhang, X. Y..(2023).Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration.DEPRESSION AND ANXIETY,2023,9. |
MLA | Tong, P.,et al."Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration".DEPRESSION AND ANXIETY 2023(2023):9. |
入库方式: OAI收割
来源:心理研究所
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。