Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones
文献类型：期刊论文
| 作者 | Hou, Xinjiao3,4; Wang, Run2,3; Zhou, Jianhui3; Li, Yuan3; Li, Jiyuan3; Liu, Hong1,3,4 ; Wang, Dechuan4; Zhou, Yu1,3
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| 刊名 | ADVANCED SYNTHESIS & CATALYSIS
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| 出版日期 | 2023-12-06 |
| 页码 | 8 |
| ISSN号 | 1615-4150 |
| 关键词 | C-H bond activation Fused heterocycles Rh(III) catalysis Ru(II) catalysis |
| DOI | 10.1002/adsc.202300897 |
| 通讯作者 | Liu, Hong(wdc@cpu.edu.cn) ; Wang, Dechuan(hliu@simm.ac.cn) ; Zhou, Yu(zhouyu@simm.ac.cn) |
| 英文摘要 | A substrate and catalyst-controlled synthetic strategy was employed to construct two distinct types of fused polycyclic heterocycles, namely pyrido[2,3,4-de]quinazolinones and indolo[1,2-c]quinazolinones. The most notable advantage of this method is its ability to rapidly generate two different polycyclic scaffolds via a simple C-H activation and subsequent cyclization cascade pathway. Specifically, sulfoxonium ylides played a crucial role in both transformations, serving as a two-carbon synthon and a one-carbon synthon, to independently construct the two fused polycyclic scaffolds through [4+2] and [4+1] annulation pathways, respectively. |
| WOS关键词 | RELAY CARBENOID FUNCTIONALIZATION ; POLYHETEROAROMATIC COMPOUNDS ; NITROGEN-HETEROCYCLES ; ACTIVATION ; ANNULATION ; QUINAZOLINE ; DERIVATIVES ; DIVERSITY ; ALKYNES ; ACCESS |
| 资助项目 | National Natural Science Foundation of China ; [82173656] ; [21977106] ; [82151219] ; [82103969] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:001114572300001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/308086]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Liu, Hong; Wang, Dechuan; Zhou, Yu |
| 作者单位 | 1.Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Pharmaceut Sci & Technol, Hangzhou 310024, Peoples R China 2.Fudan Univ, Sch Pharm, Dept Med Chem, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Dev Ctr, Shanghai 201203, Peoples R China 4.China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Xinjiao,Wang, Run,Zhou, Jianhui,et al. Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones[J]. ADVANCED SYNTHESIS & CATALYSIS,2023:8. |
| APA | Hou, Xinjiao.,Wang, Run.,Zhou, Jianhui.,Li, Yuan.,Li, Jiyuan.,...&Zhou, Yu.(2023).Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones.ADVANCED SYNTHESIS & CATALYSIS,8. |
| MLA | Hou, Xinjiao,et al."Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones".ADVANCED SYNTHESIS & CATALYSIS (2023):8. |
入库方式： OAI收割
来源：上海药物研究所
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