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Chiral Sensing of Tryptophan Enantiomers Based on the Enzyme Mimics of β-Cyclodextrin-Modified Sulfur Quantum Dots

文献类型：期刊论文

作者Jiang, Weijia1,4; He, Ran1; Lv, Han1; He, Xinheng2,3; Wang, Li1; Wei, Yanli1
刊名ACS SENSORS
出版日期2023-11-02
卷号8期号:11页码:4264-4271
关键词fluorescence recognition sulfur quantum dots nanoenzymes beta-cyclodextrin tryptophan enantiomers
ISSN号2379-3694
DOI10.1021/acssensors.3c01616
通讯作者Wang, Li(weiyanli@sxu.edu.cn) ; Wei, Yanli(wangli@sxu.edu.cn)
英文摘要Chiral recognition of amino acid plays a significant role in pharmaceutical, medical, and food science. This study describes a chiral sensing system of beta-cyclodextrin (beta-CD)-coated sulfur quantum dots (CD-SQDs) for the selective fluorescence recognition of tryptophan (Trp) enantiomers. CD-SQDs were prepared by a facile assembly fission method and could selectively recognize L-Trp by the different binding ability between L/D-Trp and beta-CD. The inclusion of L-Trp and the stereoselective catalysis of CD-SQDs enzyme mimics cause the increased fluorescence intensity of CD-SQDs, which has a linear response ranging from 10 to 500 nM and the detection limit as 2.3 nM. CD-SQDs also show great selectivity for L-Trp from the commercial compound amino acid injection. The study could provide an effective method for the chiral recognition of amino acid enantiomers based on the catalytic activity of nanoenzymes.
WOS关键词AMINO-ACIDS ; PHENYLALANINE ; RECOGNITION
资助项目Shanxi Special project for patent promotion of Shanxi Province[202202034] ; Modern Agro-industry Technology Research System[2023CYJSTX10] ; Shanxi Provincial Hundreds of Talents Programs[205698901008] ; Shanxi Provincial Hundreds of Talents Programs[205698901012] ; Shanxi Provincial Hundreds of Talents Programs[205698901004]
WOS研究方向Chemistry ; Science & Technology - Other Topics
语种英语
WOS记录号WOS:001109824100001
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/308188]  
专题中国科学院上海药物研究所
通讯作者Wang, Li; Wei, Yanli
作者单位1.Shanxi Univ, Inst Environm Sci, Taiyuan 030031, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, CAS Key Lab Receptor Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
4.Shanxi Univ Chinese Med, Res Ctr Neurobiol, Key Res Lab Benefiting Qi Acting Blood Circulat Me, Jinzhong 030619, Peoples R China
推荐引用方式
GB/T 7714		 Jiang, Weijia,He, Ran,Lv, Han,et al. Chiral Sensing of Tryptophan Enantiomers Based on the Enzyme Mimics of β-Cyclodextrin-Modified Sulfur Quantum Dots[J]. ACS SENSORS,2023,8(11):4264-4271.
APA Jiang, Weijia,He, Ran,Lv, Han,He, Xinheng,Wang, Li,&Wei, Yanli.(2023).Chiral Sensing of Tryptophan Enantiomers Based on the Enzyme Mimics of β-Cyclodextrin-Modified Sulfur Quantum Dots.ACS SENSORS,8(11),4264-4271.
MLA Jiang, Weijia,et al."Chiral Sensing of Tryptophan Enantiomers Based on the Enzyme Mimics of β-Cyclodextrin-Modified Sulfur Quantum Dots".ACS SENSORS 8.11(2023):4264-4271.

入库方式： OAI收割

来源：上海药物研究所

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