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  2. 烟台海岸带研究所
  3. 中国科学院烟台海岸带研究所
  4. 中科院海岸带环境过程与生态修复重点实验室
Responsive fluorescent probes for cellular microenvironment and redox small biomolecules

文献类型：期刊论文

作者Zhang, Li1,3; Zhang, Liangwei3; Zhang, Xia1,2,3; Zhao, Yang3; Fang, Shujing3; You, Jinmao5; Chen, Lingxin3,4
刊名TRAC-TRENDS IN ANALYTICAL CHEMISTRY
出版日期2023-12-01
卷号169页码:23
ISSN号0165-9936
关键词Response fluorescent probes Microenvironment Redox small biomolecules Specific recognition sites Design strategy Biological applications
DOI10.1016/j.trac.2023.117377
通讯作者Zhang, Liangwei(liangweizhang@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要The living system is critically depended on the inner microenvironment and redox small biomolecules to maintain the normal physiological processes. Consequently, tracing and monitoring the functional mechanism of the microenvironment and redox small biomolecules remain of extraordinary significance. Fluorescent probes have emerged for bearing the important tasks of biosensing and bioimaging with superior fluorescence signal and superb targeting specificity. In this review, we focus on the responsive fluorescent probes of microenvironment-related parameters of pH, viscosity and hypoxia, and redox small biomolecules of the reactive oxygen species, reactive nitrogen species, reactive sulfur specie, respectively. Each category is firstly devoted generally functions of the target molecule properties, and then discuss the design strategy according to the specific recognition groups, as well as biological applications. We hope our review will provide useful guidance in development advanced fluorescence probe for monitoring the microenvironments and redox small biomolecules to reveal their special biological processes.
WOS关键词LARGE STOKES SHIFT ; LIVING CELLS ; HYDROGEN-SULFIDE ; SUPEROXIDE ANION ; RATIONAL DESIGN ; REACTIVE OXYGEN ; RECENT PROGRESS ; ENDOPLASMIC-RETICULUM ; FLUOROGENIC PROBE ; MOLECULE PROBE
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001102342300001
资助机构National Natural Science Foundation of China ; Program of Youth Innovation Promotion Association, CAS ; Taishan Scholar Project Special Funding ; major innovation fund of Shandong Province
源URL[http://ir.yic.ac.cn/handle/133337/33216]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Zhang, Liangwei; Chen, Lingxin
作者单位1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
4.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China
5.Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Li,Zhang, Liangwei,Zhang, Xia,et al. Responsive fluorescent probes for cellular microenvironment and redox small biomolecules[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2023,169:23.
APA Zhang, Li.,Zhang, Liangwei.,Zhang, Xia.,Zhao, Yang.,Fang, Shujing.,...&Chen, Lingxin.(2023).Responsive fluorescent probes for cellular microenvironment and redox small biomolecules.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,169,23.
MLA Zhang, Li,et al."Responsive fluorescent probes for cellular microenvironment and redox small biomolecules".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 169(2023):23.

入库方式： OAI收割

来源：烟台海岸带研究所

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