中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 烟台海岸带研究所
  3. 中国科学院烟台海岸带研究所
  4. 中科院海岸带环境过程与生态修复重点实验室
Development of fluorescent probes with specific recognition moiety for hydrogen polysulfide

文献类型：期刊论文

作者Zhang, Xia1,2,6; Yang, Yang2; Zhang, Li1,2; Liu, Shudi3; Song, Zhihua4; Zhang, Liangwei2; You, Jinmao5; Chen, Lingxin2
刊名TALANTA
出版日期2024-02-01
卷号268页码:8
ISSN号0039-9140
关键词New recognition moiety H2Sn Probe design Fluorescent probe Living cells imaging
DOI10.1016/j.talanta.2023.125293
通讯作者Zhang, Liangwei(liangweizhang@yic.ac.cn) ; You, Jinmao(jmyou6304@163.com) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要Hydrogen polysulfide (H2Sn, n > 1) is an important component of reactive sulfur species (RSS), which is an important substance for maintaining the redox balance in cells. However, limited recognition moieties are available for hydrogen polysulfide probe design. In this study, we have constructed a small library containing several organic molecules to explore a new specific recognition moiety for H2Sn fluorescent probe design. To validate the discovery, two fluorescent probes, 7 and BCC, were further developed based on coumarin and its derivative. The probes exhibited desirable specificity for H2Sn monitoring, which can be used for detecting H2Sn in solution and cells. The new specific recognition moiety for H2Sn fluorescent probe design discovered in this work has certain guiding significance for development of H2Sn probes exploring biological roles in the future.
WOS关键词LIVING CELLS ; SULFIDE ; LIPOPOLYSACCHARIDE ; PERSULFIDES
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001104798600001
资助机构National Natural Science Foundation of China ; Major Innovation Fund of Shandong Province ; Program of Youth Innovation Promotion Association, CAS ; Taishan Scholar Project Special Funding
源URL[http://ir.yic.ac.cn/handle/133337/33240]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Zhang, Liangwei; You, Jinmao; Chen, Lingxin
作者单位1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
3.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China
4.Yantai Univ, Sch Pharm, Yantai 264005, Peoples R China
5.Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China
6.Binzhou Med Univ, Dept Biochem & Mol Biol, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Xia,Yang, Yang,Zhang, Li,et al. Development of fluorescent probes with specific recognition moiety for hydrogen polysulfide[J]. TALANTA,2024,268:8.
APA Zhang, Xia.,Yang, Yang.,Zhang, Li.,Liu, Shudi.,Song, Zhihua.,...&Chen, Lingxin.(2024).Development of fluorescent probes with specific recognition moiety for hydrogen polysulfide.TALANTA,268,8.
MLA Zhang, Xia,et al."Development of fluorescent probes with specific recognition moiety for hydrogen polysulfide".TALANTA 268(2024):8.

入库方式： OAI收割

来源：烟台海岸带研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。