Molecular imprinting-based indirect fluorescence detection strategy implemented on paper chip for non-fluorescent microcystin
文献类型：期刊论文
| 作者 | Li, Bowei1,2 ; Qi, Ji1,2; Liu, Feng1; Zhao, Rongfang1,2; Arabi, Maryam1,2; Ostovan, Abbas1,2; Song, Jinming2,3,4; Wang, Xiaoyan5; Zhang, Zhiyang1,2; Chen, Lingxin1,2,6
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| 刊名 | NATURE COMMUNICATIONS
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| 出版日期 | 2023-10-17 |
| 卷号 | 14期号:1页码:12 |
| DOI | 10.1038/s41467-023-42244-z |
| 通讯作者 | Qi, Ji(jqi@yic.ac.cn) ; Song, Jinming(jmsong@qdio.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn) |
| 英文摘要 | Fluorescence analysis is a fast and sensitive method, and has great potential application in trace detection of environmental toxins. However, many important environmental toxins are non-fluorescent substances, and it is still a challenge to construct a fluorescence detection method for non-fluorescent substances. Here, by means of charge transfer effect and smart molecular imprinting technology, we report a sensitive indirect fluorescent sensing mechanism (IFSM) and microcystin (MC-RR) is selected as a model target. A molecular imprinted thin film is immobilized on the surface of zinc ferrite nanoparticles (ZnFe2O4 NPs) by using arginine, a dummy fragment of MC-RR. By implementation of IFSM on the paper-based microfluidic chip, a versatile platform for the quantitative assay of MC-RR is developed at trace level (the limit of detection of 0.43 mu g/L and time of 20 min) in real water samples without any pretreatment. Importantly, the proposed IFSM can be easily modified and extended for the wide variety of species which lack direct interaction with the fluorescent substrate. This work offers the potential possibility to meet the requirements for the on-site analysis and may explore potential applications of molecularly imprinted fluorescent sensors. |
| WOS关键词 | POLYMER NANOPARTICLES ; MICROFLUIDIC CHIP ; LR ; IMMUNOASSAY ; APTASENSOR ; DOTS |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001086900900010 |
| 资助机构 | This work was financially supported by the National Natural Science Foundation of China (Grant No. 22106179 to J.Q., 42376188 to B.L., 22376216 to L.C., 41776110 to B.L. and 22374162 to M.A.), Shandong Provincial Natural Science Foundation Key Project (ZR2 ; National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project ; Key Technology Projects of Equipment for Cold-seep Ecosystem Research ; Chinese Academy of Sciences President's International Fellowship Initiative ; Taishan Scholar Project Special Funding |
| 源URL | [http://ir.yic.ac.cn/handle/133337/33264]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 |
| 通讯作者 | Qi, Ji; Song, Jinming; Chen, Lingxin |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 5.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 6.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Bowei,Qi, Ji,Liu, Feng,et al. Molecular imprinting-based indirect fluorescence detection strategy implemented on paper chip for non-fluorescent microcystin[J]. NATURE COMMUNICATIONS,2023,14(1):12. |
| APA | Li, Bowei.,Qi, Ji.,Liu, Feng.,Zhao, Rongfang.,Arabi, Maryam.,...&Chen, Lingxin.(2023).Molecular imprinting-based indirect fluorescence detection strategy implemented on paper chip for non-fluorescent microcystin.NATURE COMMUNICATIONS,14(1),12. |
| MLA | Li, Bowei,et al."Molecular imprinting-based indirect fluorescence detection strategy implemented on paper chip for non-fluorescent microcystin".NATURE COMMUNICATIONS 14.1(2023):12. |
入库方式： OAI收割
来源：烟台海岸带研究所
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