Phenolic Acid Functional Quaternized Chitooligosaccharide Derivatives: Preparation, Characterization, Antioxidant, Antibacterial, and Antifungal Activity
文献类型：期刊论文
| 作者 | Sun, Yan1,2,3; Cui, Jingmin1,2; Tian, Liguang4; Mi, Yingqi1,2,3; Guo, Zhanyong1,2
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| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2023-10-01 |
| 卷号 | 21期号:10页码:22 |
| 关键词 | chitooligosaccharide chitooligosaccharide quaternary ammonium salt derivatives phenolic acid antioxidant activity antibacterial activity antifungal activity |
| DOI | 10.3390/md21100535 |
| 通讯作者 | Guo, Zhanyong(zhanyongguo@hotmail.com) |
| 英文摘要 | As a promising biological material, chitooligosaccharide (COS) has attracted increasing attention because of its unique biological activities. In this study, fourteen novel phenolic acid functional COS derivatives were successfully prepared using two facile methods. The structures of derivatives were characterized by FT-IR and 1H NMR spectra. The in vitro antioxidant activity experiment results demonstrated that the derivatives presented stronger 1,1-Diphenyl-2-picryl-hydrazyl (DPPH), superoxide, hydroxyl radical scavenging activity and reducing power, especially the N,N,N-trimethylated chitooligosaccharide gallic acid salt (GLTMC), gallic acid esterified N,N,N-trimethylated chitooligosaccharide (GL-TMC) and caffeic acid N,N,N-trimethylated chitooligosaccharide (CFTMC) derivatives. Furthermore, the antifungal assay was carried out and the results indicated that the salicylic acid esterified N,N,N-trimethylated chitooligosaccharide (SY-TMC) had much better inhibitory activity against Botrytis cinerea and Fusarium graminearum. Additionally, the results of the bacteriostasis experiment showed that the caffeic acid esterified N,N,N-trimethylated chitooligosaccharide (CF-TMC) had the potential ability to inhibit Escherichia coli and Staphylococcus aureus bacteria. Altogether, this study may provide a neoteric method to produce COS derivatives with significantly increased biological activities, which have potential use in food, medicine, and health care products and other related industries. |
| WOS关键词 | CARBOXYMETHYL CHITOSAN ; STRESS |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001093593300001 |
| 资助机构 | The authors thank the support of the Yellow River Delta Saline-Alkali Agroecosystem Observation and Research Station. |
| 源URL | [http://ir.yic.ac.cn/handle/133337/33279]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Guo, Zhanyong |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 3.Shandong Saline Alkali Land Modern Agr Co, Dongying 257300, Peoples R China 4.Yantai Agr Technol Extens Ctr, Yantai 265499, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Yan,Cui, Jingmin,Tian, Liguang,et al. Phenolic Acid Functional Quaternized Chitooligosaccharide Derivatives: Preparation, Characterization, Antioxidant, Antibacterial, and Antifungal Activity[J]. MARINE DRUGS,2023,21(10):22. |
| APA | Sun, Yan,Cui, Jingmin,Tian, Liguang,Mi, Yingqi,&Guo, Zhanyong.(2023).Phenolic Acid Functional Quaternized Chitooligosaccharide Derivatives: Preparation, Characterization, Antioxidant, Antibacterial, and Antifungal Activity.MARINE DRUGS,21(10),22. |
| MLA | Sun, Yan,et al."Phenolic Acid Functional Quaternized Chitooligosaccharide Derivatives: Preparation, Characterization, Antioxidant, Antibacterial, and Antifungal Activity".MARINE DRUGS 21.10(2023):22. |
入库方式： OAI收割
来源：烟台海岸带研究所
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