Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes
文献类型：期刊论文
| 作者 | Yu, Tieying1,2; Ning, Junhao1; Chen, Min1 ; Wang, Yuan1,2; Liu, Guilong3; Wang, Quanchao1; Xu, Xin3; Wang, Chunde1,2,5; Lu, Xia1,4
|
| 刊名 | AQUACULTURE REPORTS
 |
| 出版日期 | 2023-08-01 |
| 卷号 | 31页码:12 |
| ISSN号 | 2352-5134 |
| 关键词 | Hermaphroditic Argopecten scallops Hybrid sterility MtDNA mutation Energy deficiency Gene expression |
| DOI | 10.1016/j.aqrep.2023.101652 |
| 通讯作者 | Lu, Xia(xialu@yic.ac.cn) |
| 英文摘要 | Bay scallops (Argopecten irradians) are a commercially important bivalve species for fisheries and aquaculture in China, the USA, Peru and Chile, but their small size and serious inbreeding depression restrict the sustainable development of their aquaculture. We successfully hybridized bay scallops with Peruvian scallops (Argopecten purpuratus), and the F1 hybrids showed significant heterosis in growth, but the majority of them were sterile. Nevertheless, Argopecten scallops are typical hermaphroditic animals, resulting in a low proportion of interspecific hybrids. Hybrid sterility restricts the utilization of Argopecten scallop resources and causes reproductive isolation in speciation. However, the underlying mechanism of hybrid sterility remains unexplored in hermaphroditic scallops. In this study, we investigated the mechanism of hybrid sterility in hermaphroditic Argopecten scallops by examining mutations in mitochondrial genes and the expression of nuclear genes. Our results showed that the ATP content in the gonads of F1 hybrid scallops was significantly lower than that in their parents, indicating that energy deficiency may be an immediate cause of sterility in F1 hybrid scallops. Thirteen SNPs were detected in five mitochondrial genes of F1 hybrids, and 92.3% of which were transitions that could change the hydrophobicity of amino acids and protein structures, and the allele frequencies of the SNP loci were significantly different between sterile hybrids and fertile scallops. Abnormal interaction between the mitochondrial and nuclear genes might contribute to hybrid sterility through the following pathways: (1) inhibition of oocyte maturation by enhanced expression of Mfn2; (2) cell cycle arrest in G1 phase of oocytes by inhibited expression of CDK2; (3) cell apoptosis induced by mitochondrial apoptosis; (4) insufficient energy supply from abnormal mitochondria, and (5) mitochondrial dysfunction resulting from abnormal expression of other nuclear genes. The present results provide more information for understanding the mechanism of hybrid sterility in hermaphroditic animals and benefit extensive hybrid breeding. |
| WOS关键词 | DOUBLY UNIPARENTAL INHERITANCE ; BAY SCALLOP ; INBREEDING DEPRESSION ; CELL-DEATH ; TRAITS ; DEFECTS ; MTDNA |
| WOS研究方向 | Fisheries |
| 语种 | 英语 |
| WOS记录号 | WOS:001039983700001 |
| 资助机构 | National Natural Science Foundation of China ; Earmarked Fund for Agriculture Seed Improvement Project of Shandong Province ; Scientific and Technological Project of Yantai, Shandong Province ; Ear-marked Fund for Shandong Modern Agro-Industry Technology Research System ; Science and technology smes innovation capacity improvement project in Shandong Province |
| 源URL | [http://ir.yic.ac.cn/handle/133337/33399]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Lu, Xia |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res & Dev Ctr Efficient Utilizat Coastal Bioresour, Yantai 264003, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Yantai Spring Sea AquaSeed Ltd, Yantai 264006, Peoples R China 4.17 Chunhui Rd, Yantai, Peoples R China 5.Qingdao Agr Univ, Coll Marine Sci & Engn, Qingdao 266109, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Tieying,Ning, Junhao,Chen, Min,et al. Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes[J]. AQUACULTURE REPORTS,2023,31:12. |
| APA | Yu, Tieying.,Ning, Junhao.,Chen, Min.,Wang, Yuan.,Liu, Guilong.,...&Lu, Xia.(2023).Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes.AQUACULTURE REPORTS,31,12. |
| MLA | Yu, Tieying,et al."Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes".AQUACULTURE REPORTS 31(2023):12. |
入库方式： OAI收割
来源：烟台海岸带研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。