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Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of & alpha;-tocopherol

文献类型：期刊论文

作者Yuan, Yuting1,3,4; Wang, Zhenhua2; Su, Shengjia5; Lin, Conghao2; Mi, Yingqi3,4; Tan, Wenqiang3,4; Guo, Zhanyong1,3,4
刊名FOOD CHEMISTRY
出版日期2023-12-15
卷号429页码:11
ISSN号0308-8146
关键词Amphiphilic low molecular weight chitosan derivative Photostability Self-assembled cationic micelle Solubility Sustained release behavior & alpha -tocopherol
DOI10.1016/j.foodchem.2023.136886
通讯作者Tan, Wenqiang(wqtan@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要New amphiphilic low molecular weight chitosan-graft-nicotinic acid bearing decyl groups (LCND) was synthesized by two-step reaction and spontaneously assembled into cationic micelle by ultra-sonication method to improve water solubility and photostability properties of a-tocopherol. The chemical structure of LCND was characterized and physical properties of cationic micelle were evaluated. Results displayed that cationic micelle exhibited strong self-assemble ability with nanoscale spherical morphology and showed best loading ability with loading content of 18.50% when the feeding ratio of LCND to a-tocopherol reached 10:3. Meanwhile, the greatly enhanced water solubility, photostability and sustained release behavior of a-tocopherol in cationic micelle were observed. The cumulative release of a-tocopherol in cationic micelle reached up 82.18% within 96 h while free a-tocopherol was completely released within 10 h. Additionally, release kinetics models were also fitted. The LCND cationic micelle could be promising nanocarrier for improving the physicochemical properties of a-tocopherol in food fields.
WOS关键词ALPHA-TOCOPHEROL ; PHOTOSTABILITY ; NANOPARTICLES ; ENCAPSULATION ; DERIVATIVES ; DELIVERY
WOS研究方向Chemistry ; Food Science & Technology ; Nutrition & Dietetics
语种英语
WOS记录号WOS:001050470800001
资助机构Youth Innovation Promotion Association CAS, China ; Shandong Key Ramp;D plan, Major Scientific and Technological Innovation Project ; Science amp; Technology Specific Projects in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta
源URL[http://ir.yic.ac.cn/handle/133337/33450]  
专题海岸带生物学与生物资源利用重点实验室
海岸带生物资源高效利用研究与发展中心
通讯作者Tan, Wenqiang; Guo, Zhanyong
作者单位1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
2.Yantai Univ, Coll Life Sci, Yantai 264005, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China
5.Shandong Saline Alkali Land Modern Agr Co, Dongying 257300, Peoples R China
推荐引用方式
GB/T 7714		 Yuan, Yuting,Wang, Zhenhua,Su, Shengjia,et al. Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of & alpha;-tocopherol[J]. FOOD CHEMISTRY,2023,429:11.
APA Yuan, Yuting.,Wang, Zhenhua.,Su, Shengjia.,Lin, Conghao.,Mi, Yingqi.,...&Guo, Zhanyong.(2023).Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of & alpha;-tocopherol.FOOD CHEMISTRY,429,11.
MLA Yuan, Yuting,et al."Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of & alpha;-tocopherol".FOOD CHEMISTRY 429(2023):11.

入库方式： OAI收割

来源：烟台海岸带研究所

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