深海冷泉草酸青霉Penicillium oxalicum 13-37的化学成分研究
文献类型：期刊论文
| 作者 | 刘雅萍1,2; 方圣涛2 ; 时振振2; 季乃云2
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| 刊名 | 海洋科学
 |
| 出版日期 | 2022 |
| 卷号 | 46期号:5页码:115-121 |
| 关键词 | 深海冷泉 草酸青霉 次生代谢产物 化学成分 生物活性 |
| ISSN号 | 1000-3096 |
| 其他题名 | Chemical constituents of Penicillium oxalicum 13-37 from cold-seep sediments |
| 文献子类 | 期刊论文 |
| 英文摘要 | To enrich the structural diversity of natural products from a deep-sea cold seep, the secondary metabolites of Penicillium oxalicum 13-37, a fungus derived from cold-seep sediments, were investigated. Eleven compounds were obtained using silica gel column chromatography, reversed-phase silica gel column chromatography, Sephadex LH-20 gel column chromatography, preparative thin-layer chromatography, and semi-preparative high-performance liquid chromatography. They were identified as seco-blennolide B(1), blennolide B(2), citreorosein(3), emodine(4), isorhodoptilometrin(5), aloe-emodin(6), 2-acetylemodin(7), 11-O-acetylaloeemodin(8), phaseolorin I(9), penitholabene(10), and paecilomycine A(11). Among them, 1 is a novel compound. Compounds 10 and 11 are known terpenoids isolated from cold seep-derived Penicillium oxalicum for the first time, and the single-crystal data of compound 10 are reported for the first time. Additionally, the activities of the new compound were tested. The results revealed that the new compound has inhibitory effects on the growth of Prorocentrum donghaiense, Chattonella marina, and Vibrio parahaemolyticus. Furthermore, compound 1 weakly inhibited Artemia salina. |
| 语种 | 中文 |
| CSCD记录号 | CSCD:7240764 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/34129]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 作者单位 | 1.中国科学院大学,北京100049 2.中国科学院烟台海岸带研究所,山东烟台264003; |
| 推荐引用方式 GB/T 7714 | 刘雅萍,方圣涛,时振振,等. 深海冷泉草酸青霉Penicillium oxalicum 13-37的化学成分研究[J]. 海洋科学,2022,46(5):115-121. |
| APA | 刘雅萍,方圣涛,时振振,&季乃云.(2022).深海冷泉草酸青霉Penicillium oxalicum 13-37的化学成分研究.海洋科学,46(5),115-121. |
| MLA | 刘雅萍,et al."深海冷泉草酸青霉Penicillium oxalicum 13-37的化学成分研究".海洋科学 46.5(2022):115-121. |
入库方式： OAI收割
来源：烟台海岸带研究所
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