新水缸潜水模型在斑马鱼焦虑及应激行为研究中的进展
文献类型：期刊论文
| 作者 | 林艾诺1,3; 李亚茜1,3; 闫志2; 李可3
|
| 刊名 | 中国实验动物学报
 |
| 出版日期 | 2023 |
| 卷号 | 31期号:4页码:514-523 |
| ISSN号 | 1005-4847 |
| 关键词 | 新型水缸 焦虑 斑马鱼 运动参数 药物筛选 |
| 其他题名 | Advances in novel tank diving test for the study of anxiety and stress behaviour in zebrafish |
| 文献子类 | 期刊论文 |
| 英文摘要 | The novel tank diving test is a drug screening paradigm between in vivo and cellular assays, which is specially designed for the anxiety behavioral response of zebrafish or other small fish. This paradigm was derived from the maze model in rodents and has advantages in terms of the convenience of behavior assays. Zebrafish shares high gene homology with humans. Chemically triggered anxiety and aggression in zebrafish are closely related to the hypothalamicpituitary- renal gland axis in the endocrine system, which is parallel to the effect of the hypothalamic-pituitary-adrenal axis in humans. The novel tank diving test is an efficient and reliable high-throughput behavioral screening model mainly used in studying animal sociality, addiction, sleeping, learning, and memory. The novel tank diving test has been widely used in various scenarios from initiative to continuous improvement in the previous 15 years. This article reviews the origin, measurement parameters, usage, existing problems, and perspectives of this paradigm compared with the light/dark test to broaden the anxiety behavior evaluation paradigm and application scope. |
| 语种 | 中文 |
| CSCD记录号 | CSCD:7487672 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/34277]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 作者单位 | 1.中国科学院大学,北京101408; 2.烟台大学,山东烟台264005 3.中国科学院烟台海岸带研究所,山东烟台264003; |
| 推荐引用方式 GB/T 7714 | 林艾诺,李亚茜,闫志,等. 新水缸潜水模型在斑马鱼焦虑及应激行为研究中的进展[J]. 中国实验动物学报,2023,31(4):514-523. |
| APA | 林艾诺,李亚茜,闫志,&李可.(2023).新水缸潜水模型在斑马鱼焦虑及应激行为研究中的进展.中国实验动物学报,31(4),514-523. |
| MLA | 林艾诺,et al."新水缸潜水模型在斑马鱼焦虑及应激行为研究中的进展".中国实验动物学报 31.4(2023):514-523. |
入库方式： OAI收割
来源：烟台海岸带研究所
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