中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Range adaptive value representations in schizophrenia and major depression

文献类型:期刊论文

作者Wang, Ling-ling8,9,10,11; Lui, Simon S. Y.7; So, Jane W. L.6; Hu, Hui-xin5,9,10,11; Chu, Min-yi4; Cheng, Koi-Man6; Li, Shuai-biao4; Le, Bei-lin9,10,11; Lv, Qin-yu3,4; Yi, Zheng-hui2,4
刊名ASIAN JOURNAL OF PSYCHIATRY
出版日期2024-02-01
卷号92页码:8
通讯作者邮箱rckchan@psych.nc.cn (r.c.k. chan)
ISSN号1876-2018
关键词Range adaptation Reward processing Anhedonia Amotivation Transdiagnostic
DOI10.1016/j.ajp.2023.103880
产权排序1
文献子类实证研究
英文摘要

Anhedonia and amotivation are core symptoms of schizophrenia (SCZ) and major depressive disorder (MDD). Reward processing involves constructing and contrasting the representations for expected value (EV) and outcome value (OV) of a given stimulus, a phenomenon termed range adaptation. Impaired range adaptation can lead to anhedonia and amotivation. This study aimed to examine range adaptation in SCZ patients and MDD patients. Fifty SCZ, 46 MDD patients and 56 controls completed the Effort-based Pleasure Experience Task to measure EV and OV adaptation. SCZ and MDD patients showed altered range adaptation, albeit in different patterns. SCZ patients exhibited over-adaptation to OV and reduced adaptation to EV. By contrast, MDD patients exhibited diminished OV adaptation but intact EV adaptation. Both OV and EV adaptation were correlated with anhedonia and amotivation in SCZ and MDD. Taken together, our findings suggest that range adaptation is altered in both SCZ and MDD patients. Associations of OV and EV adaptation with anhedonia and amotivation were consistently found in SCZ and MDD patients. Impaired range adaptation in SCZ and MDD patients may be putative neural mechanisms and potential intervention targets for anhedonia and amotivation.

收录类别SCI
WOS关键词REWARD ; PLEASURE ; DEFICITS ; SCALE ; METAANALYSIS ; ADAPTATION ; MOTIVATION
资助项目Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences[E2CX3415CX] ; National Key Research and Development Program[2016YFC0906402] ; Philip K. H. Wong Foundation
WOS研究方向Psychiatry
语种英语
出版者ELSEVIER
WOS记录号WOS:001152913600001
资助机构Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences ; National Key Research and Development Program ; Philip K. H. Wong Foundation
源URL[http://ir.psych.ac.cn/handle/311026/46918]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Chan, Raymond C. K.
作者单位1.Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China
2.Fudan Univ, Inst Mental Hlth, Shanghai, Peoples R China
3.Fudan Univ, Huashan Hosp, Dept Psychiat, Shanghai, Peoples R China
4.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai, Peoples R China
5.Beijing Forestry Univ, Sch Humanities & Social Sci, Dept Psychol, Beijing, Peoples R China
6.Castle Peak Hosp, Hong Kong, Peoples R China
7.Univ Hong Kong, Sch Clin Med, Dept Psychiat, Hong Kong, Peoples R China
8.Shanghai Normal Univ, Sch Psychol, Shanghai, Peoples R China
9.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
10.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Wang, Ling-ling,Lui, Simon S. Y.,So, Jane W. L.,et al. Range adaptive value representations in schizophrenia and major depression[J]. ASIAN JOURNAL OF PSYCHIATRY,2024,92:8.
APA Wang, Ling-ling.,Lui, Simon S. Y..,So, Jane W. L..,Hu, Hui-xin.,Chu, Min-yi.,...&Chan, Raymond C. K..(2024).Range adaptive value representations in schizophrenia and major depression.ASIAN JOURNAL OF PSYCHIATRY,92,8.
MLA Wang, Ling-ling,et al."Range adaptive value representations in schizophrenia and major depression".ASIAN JOURNAL OF PSYCHIATRY 92(2024):8.

入库方式: OAI收割

来源:心理研究所

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