中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 植物研究所
  3. 中国科学院植物研究所
  4. 中科院植物分子生理学重点实验室
Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis

文献类型：期刊论文

作者Zhang, Lu2; Thapa Magar, Madhu Shudan2,3; Wang, Yanning2; Cheng, Youfa2,4
刊名PLANT MOLECULAR BIOLOGY
出版日期2022
卷号110期号:1-2页码:1-12
ISSN号0167-4412
关键词S-acylation Protein S-acyl transferases CESA3 Cellulose biosynthesis AtTIP1 AtPAT24
DOI10.1007/s11103-022-01283-8
文献子类Article
英文摘要Key message AtTIP1 physically and genetically interacts with AtCESA3. AtCESA3 undergoes S-acylation, possibly mediated by AtTIP1, suggesting a specific role of AtTIP1 in cellulose biosynthesis and plant development. S-acylation is a reversible post-translational lipid modification of proteins catalyzed by protein S-acyl transferases (PATs). S-acylation is important for various biological molecular mechanisms including cellulose biosynthesis. Cellulose is synthesized by the cellulose synthase A (CESA) complexes (CSCs) at the plasma membrane. However, specific PAT involving in cellulose biosynthesis has not been identified and the precise mechanism by which PAT regulates the CESAs is largely unknown. Here, we report isolation of tip1-5, an allele of Tip Growth Defective1 (AtTIP1/AtPAT24) with a premature stop codon. tip1-5 genetically interacts with ixr1-2, a point mutant of AtCESA3 which encodes a catalytic subunit of CSC synthesizing primary wall cellulose. We show that AtTIP1 physically interacts with AtCESA3. AtCESA3 undergoes S-acylation, which is possibly mediated by AtTIP1, suggesting a functional relationship between AtTIP1 and AtCESA3. Moreover, the interfascicular fiber cells in the primary inflorescence stems of tip1-5 ixr1-2 double mutant contain thinner cell walls and significantly less crystalline cellulose compared to the single mutants. These results highlight the positive regulation of AtTIP1 in cellulose biosynthesis, and a specific role of AtPAT in plant development.
学科主题Biochemistry & Molecular Biology ; Plant Sciences
电子版国际标准刊号1573-5028
出版地DORDRECHT
WOS关键词PROTEIN ; COMPLEXES ; MUTANT
WOS研究方向Science Citation Index Expanded (SCI-EXPANDED)
语种英语
出版者SPRINGER
WOS记录号WOS:000802059600001
资助机构National Natural Science Foundation of China (NSFC) [31970309, 31171389] ; National Key Research and Development Program of China [2016YFD0100400] ; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA26030302] ; STS Program of the Chinese Academy of Sciences [KFJ-STS-ZDTP-076] ; CAS-TWAS President's Fellowship program
源URL[http://ir.ibcas.ac.cn/handle/2S10CLM1/28463]  
专题中科院植物分子生理学重点实验室
作者单位1.Chinese Acad Sci, Innovat Acad Seed Design, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Govt Nepal, Dept Plant Resources, Minist Forests & Environm, Kathmandu 44600, Nepal
推荐引用方式
GB/T 7714		 Zhang, Lu,Thapa Magar, Madhu Shudan,Wang, Yanning,et al. Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis[J]. PLANT MOLECULAR BIOLOGY,2022,110(1-2):1-12.
APA Zhang, Lu,Thapa Magar, Madhu Shudan,Wang, Yanning,&Cheng, Youfa.(2022).Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis.PLANT MOLECULAR BIOLOGY,110(1-2),1-12.
MLA Zhang, Lu,et al."Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis".PLANT MOLECULAR BIOLOGY 110.1-2(2022):1-12.

入库方式： OAI收割

来源：植物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。