Phytochemical Screening, Antimicrobial, Antipellicle and Antibiofilm Activities of the Root of Alpine Medicinal Plant (Arnebia euchroma (Royle) IMJohnst.)
文献类型：期刊论文
| 作者 | Ullah, Barkat; Hassan, Shahana; Khan, Muhammad Nauman; Razzaq, Abdul; Al-Sadoon, Mohammad Khalid; Wahab, Sana2; Kaplan, Alevcan3; Celikoglu, Umut4; Razak, Sarah Abdul5; Ozdemir, Fethi Ahmet6 |
| 刊名 | POLISH JOURNAL OF ENVIRONMENTAL STUDIES
 |
| 出版日期 | 2024 |
| 卷号 | 33期号:1页码:425-442 |
| 关键词 | Antimicrobial activity antipellicle and antibiofilm activity phytochemicals AgNPs A. euchroma |
| DOI | 10.15244/pjoes/171298 |
| 产权排序 | 8 |
| 英文摘要 | This study aims to analyze the phytochemical and antimicrobial-related assays including antibacterial, antifungal, antipellicle, and antibiofilm potential of the root of an alpine medicinal plant (Arnebia euchroma (Royle) I.M.Johnst). Ethanolic, methyl acetate, chloroform, and aqueous extracts of root parts of the A. euchroma plant were prepared. The active metabolites of the root part of the plant were evaluated both qualitatively and quantitatively by GC-MS and HPLC techniques, using ethanolic extract. The antimicrobial potential of A. euchroma was investigated using crude extract, fractions, and AgNPs of the A. euchroma root against two Gram-positive bacteria (Enterococcus, Staphylococcus aureus) four Gram-negative bacteria (Salmonella typhi, Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris) and five fungal strains (Rhizoctonia, Cuneate fasciculus, Aspergillus niger, Fusarium oxysporum, and Candida auris). All the bacterial strains showed sensitivity toward all the fractions (ethanolic crude, chloroform, aqueous, and methyl acetate) and AgNPs. While S. typhi was found the most susceptible, P. vulgaris was most resistant to all extracts and AgNPs. The case of anti-biofilm potential, the S. typhi and Enterococcus were shown to be most susceptible, these bacteria formed biofilm which was disrupted completely by the extracts. Among the fungal strains F. oxysporum and A. niger were the most susceptible and C. fasciculus was the most resistant fungi. All extracts, including ethanolic extract, chloroform, aqueous, and methyl acetate, at concentrations of 12.5 mu g/mL and 16 mu g/mL and AgNPs showed anti-pellicle activity against S. typhi, Rhizoctonia, and A. niger. Dose-dependent trend in all bioassays was noted. The ethanolic crude and chloroform extracts were the most active followed by methyl acetate and then aqueous extracts. The phytochemical analysis revealed that carbohydrates, alkaloids, saponins, phenols, tannins, proteins, and flavonoids were found in the plant while terpenoids were absent. The present study highlights that root of the A. euchroma is rich in various types of bioactive phytochemicals, which may be responsible for anti-microbial activities toward the tested pathogenic of bacterial and fungal strains. Our results suggest and confirm A. euchroma extracts could be used economically as a valuable bioproduct with new functional properties in the further drug development and pharmaceutical industries. |
| WOS关键词 | SILVER NANOPARTICLES ; BIOFILM FORMATION ; GREEN SYNTHESIS ; EXTRACTS ; L. ; GROWTH ; LEAVES ; HPLC |
| WOS研究方向 | Environmental Sciences & Ecology |
| WOS记录号 | WOS:001129069800009 |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/201674]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 作者单位 | 1.Islamia Coll Peshawar, Dept Bot, Peshawar 25120, Pakistan 2.King Saud Univ, Coll Sci, Dept Zool, POB 2455, Riyadh 11451, Saudi Arabia 3.Quaid I Azam Univ, Dept Plant Sci, Islamabad 45320, Pakistan 4.Batman Univ Batman, Sason Vocat Sch, Dept Crop & Anim Prod, TR-72060 Batman, Turkiye 5.Amasya Univ, Fac Arts & Sci, Dept Chem, TR-05100 Amasya, Turkiye 6.Univ Malaya, Inst Biol Sci, Fac Sci, Kuala Lumpur 50603, Malaysia 7.Bingol Univ, Fac Sci & Art, Dept Mol Biol & Genet, TR-12000 Bingol, Turkiye 8.Univ Punjab, Inst Bot, Lahore 54590, Pakistan 9.Univ Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing, Peoples R China 10.Univ Malakand, Dept Bot, Lower Dir, Chakdara 18800, Khyber Pakhtunk, Pakistan |
| 推荐引用方式 GB/T 7714 | Ullah, Barkat,Hassan, Shahana,Khan, Muhammad Nauman,et al. Phytochemical Screening, Antimicrobial, Antipellicle and Antibiofilm Activities of the Root of Alpine Medicinal Plant (Arnebia euchroma (Royle) IMJohnst.)[J]. POLISH JOURNAL OF ENVIRONMENTAL STUDIES,2024,33(1):425-442. |
| APA | Ullah, Barkat.,Hassan, Shahana.,Khan, Muhammad Nauman.,Razzaq, Abdul.,Al-Sadoon, Mohammad Khalid.,...&Darwish, Doaa Bahaa Eldin.(2024).Phytochemical Screening, Antimicrobial, Antipellicle and Antibiofilm Activities of the Root of Alpine Medicinal Plant (Arnebia euchroma (Royle) IMJohnst.).POLISH JOURNAL OF ENVIRONMENTAL STUDIES,33(1),425-442. |
| MLA | Ullah, Barkat,et al."Phytochemical Screening, Antimicrobial, Antipellicle and Antibiofilm Activities of the Root of Alpine Medicinal Plant (Arnebia euchroma (Royle) IMJohnst.)".POLISH JOURNAL OF ENVIRONMENTAL STUDIES 33.1(2024):425-442. |
入库方式： OAI收割
来源：地理科学与资源研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。