Gut-brain axis interacts with immunomodulation in inflammatory bowel disease
文献类型：期刊论文
| 作者 | Ye, Xianglu1; Zhang, Miao4,5; Zhang, Ning2,5; Wei, Hai1,2; Wang, Bing2,3 |
| 刊名 | BIOCHEMICAL PHARMACOLOGY
 |
| 出版日期 | 2024 |
| 卷号 | 219页码:8 |
| ISSN号 | 0006-2952 |
| 关键词 | IBD Gut-brain axis Immunomodulation Receptors Lymphocytes |
| DOI | 10.1016/j.bcp.2023.115949 |
| 通讯作者 | Zhang, Ning(ningzh18@126.com) ; Wei, Hai(wei_hai@hotmail.com) ; Wang, Bing(bwang@simm.ac.cn) |
| 英文摘要 | The brain and the gastrointestinal (GI) tract are important sensory organs in the body and the two-way interaction that exists between them regulates key physiological and homeostatic functions. A growing body of research suggests that this bidirectional communication influences the development and progression of functional GI disorders and plays an important role in the treatment of central nervous system (CNS) disorders. Inflammatory bowel disease (IBD) is a classic intestinal disorder with a high prevalence but still unclear pathogenesis that has been widely discussed in recent years. However, in the studies available to date, we find that many authors have chosen to discuss the influence of the brain on intestinal disorders from the top down, starting with physical and psychological disorders. Coming very naturally, based on these substantial research evidence, we focus on exploring the links between bidirectional communication in the gut-brain axis and IBD, and highlight the role of the gut microbiota, vagus nerve (VN), receptors and immune cells involved in regulating IBD through the gut-brain axis in this review. |
| WOS关键词 | ACTIVE ULCERATIVE-COLITIS ; TOLL-LIKE RECEPTOR-5 ; REGULATORY T-CELLS ; ENDOCANNABINOID SYSTEM ; VAGUS NERVE ; MACROPHAGE POLARIZATION ; INTESTINAL MICROBIOTA ; CANNABINOID RECEPTORS ; CROHNS-DISEASE ; IMMUNE-SYSTEM |
| 资助项目 | Program of Shanghai Committee of Science and Technology, China[21ZR1475200] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:001140137000001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/308678]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhang, Ning; Wei, Hai; Wang, Bing |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Integrat Med Res, Shanghai 201203, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Expt Ctr Sci & Technol, 1200 Cai lun Rd, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Ctr Pharmaceut Res, Shanghai Inst Mat Med, 501 Hai ke Rd, Shanghai 201203, Peoples R China 4.Shanghai Univ Tradit Chinese Med, Expt Ctr Sci & Technol, Shanghai 201203, Peoples R China 5.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ye, Xianglu,Zhang, Miao,Zhang, Ning,et al. Gut-brain axis interacts with immunomodulation in inflammatory bowel disease[J]. BIOCHEMICAL PHARMACOLOGY,2024,219:8. |
| APA | Ye, Xianglu,Zhang, Miao,Zhang, Ning,Wei, Hai,&Wang, Bing.(2024).Gut-brain axis interacts with immunomodulation in inflammatory bowel disease.BIOCHEMICAL PHARMACOLOGY,219,8. |
| MLA | Ye, Xianglu,et al."Gut-brain axis interacts with immunomodulation in inflammatory bowel disease".BIOCHEMICAL PHARMACOLOGY 219(2024):8. |
入库方式： OAI收割
来源：上海药物研究所
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