Synthesis of 2-amino-9H-chromeno[2,3-d]thiazol-9-ones with anti-inflammatory activity via cascade reactions of 2-amino-3 iodochromones with amines and carbon disulfide
文献类型：期刊论文
| 作者 | Tan, Jiangtao2,3; He, Yifan2,3; Lin, Yu3; Zhong, Yuanchen3; He, Shijun1,3 ; Zuo, Jianping2,3; Yang, Chunhao2,3
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2024-01-17 |
| 卷号 | 14期号:5页码:3158-3162 |
| DOI | 10.1039/d3ra07209f |
| 通讯作者 | He, Shijun(heshijun@shutcm.edu.cn) ; Yang, Chunhao(chyang@simm.ac.cn) |
| 英文摘要 | A simple and efficient synthetic approach to 2-amino-9H-chromeno[2,3-d]thiazol-9-ones via copper-promoted cascade reactions was developed. The reaction employed easily available 2-amino-3-iodochromones and amines as substrates and the targeting tricyclic compounds could be obtained with moderate to good yields. Even more important, several synthesized compounds exhibited potent anti-inflammatory activities, which suggested that this protocol may provide valuable hits for drug development in the future. |
| WOS关键词 | BENZOTHIAZOLES ; CHROMONES ; SCAFFOLD ; AGENT |
| 资助项目 | Science and Technology Commission of Shanghai Municipality[18431907100] ; Science and Technology Commission of Shanghai Municipality[SIMM2103ZZ-03] ; State Key Laboratory of Drug Research Program |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:001145495400001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/308778]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | He, Shijun; Yang, Chunhao |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Innovat Res Inst Tradit Chinese Med, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Sch Pharm, 19A YuquanRoad, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat, State Key Lab Drug Res, Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tan, Jiangtao,He, Yifan,Lin, Yu,et al. Synthesis of 2-amino-9H-chromeno[2,3-d]thiazol-9-ones with anti-inflammatory activity via cascade reactions of 2-amino-3 iodochromones with amines and carbon disulfide[J]. RSC ADVANCES,2024,14(5):3158-3162. |
| APA | Tan, Jiangtao.,He, Yifan.,Lin, Yu.,Zhong, Yuanchen.,He, Shijun.,...&Yang, Chunhao.(2024).Synthesis of 2-amino-9H-chromeno[2,3-d]thiazol-9-ones with anti-inflammatory activity via cascade reactions of 2-amino-3 iodochromones with amines and carbon disulfide.RSC ADVANCES,14(5),3158-3162. |
| MLA | Tan, Jiangtao,et al."Synthesis of 2-amino-9H-chromeno[2,3-d]thiazol-9-ones with anti-inflammatory activity via cascade reactions of 2-amino-3 iodochromones with amines and carbon disulfide".RSC ADVANCES 14.5(2024):3158-3162. |
入库方式： OAI收割
来源：上海药物研究所
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