Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-Glycosides from Glycals
文献类型：期刊论文
| 作者 | Zeng, Mingjie1,3; Yu, Changyue1; Wang, Yibing1; Wang, Jingjing1; Wang, Jiang1,2 ; Liu, Hong1,3
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| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2023-05-22 |
| 卷号 | 62期号:22页码:6 |
| 关键词 | Cobalt Catalysis C(sp(3))-C(sp(3)) Coupling beta-Configuration 2-Deoxy-C-Glycosides Radical Reactions |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.202300424 |
| 通讯作者 | Wang, Jiang(jwang@lglab.ac.cn) ; Liu, Hong(hliu@simm.ac.cn) |
| 英文摘要 | We report a ligand-controlled Co-II-catalyzed C(sp(3))-C(sp(3)) coupling hydroalkylation for direct and beta-selective synthesis of 2-deoxy-C-glycosides from glycals. This reaction proceeds by a radical pathway for alkyl halide activation and is beta-selective through ligand control. This approach may inspire the development of further stereoselective coupling reactions with potential application in the field of carbohydrates. |
| WOS关键词 | C-GLYCOSIDES ; STRATEGY |
| 资助项目 | National Natural Science Foundation of China[82130105] ; National Natural Science Foundation of China[82121005] ; National Natural Science Foundation of China[22177124] ; Shanghai Municipal Science and Technology Major Project ; Lingang Laboratory[LG202103-03-02] ; Lingang Laboratory[LG-GG-202204-02] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001143695500024 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309060]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Wang, Jiang; Liu, Hong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Chong Zhi Rd, Shanghai 201203, Peoples R China 2.Lingang Lab, Shanghai 200031, Peoples R China 3.China Pharmaceut Univ, 639 Longmian Ave, Nanjing 211198, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zeng, Mingjie,Yu, Changyue,Wang, Yibing,et al. Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-Glycosides from Glycals[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2023,62(22):6. |
| APA | Zeng, Mingjie,Yu, Changyue,Wang, Yibing,Wang, Jingjing,Wang, Jiang,&Liu, Hong.(2023).Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-Glycosides from Glycals.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,62(22),6. |
| MLA | Zeng, Mingjie,et al."Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-Glycosides from Glycals".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 62.22(2023):6. |
入库方式： OAI收割
来源：上海药物研究所
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