Traditional Chinese medicine for the treatment of immune-related nephropathy: A review
文献类型：期刊论文
| 作者 | Jiang, Pu1,2; Yao, Changliang1; Guo, De-an1,2
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| 刊名 | ACTA PHARMACEUTICA SINICA B
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| 出版日期 | 2024 |
| 卷号 | 14期号:1页码:38-66 |
| 关键词 | IgA nephropathy Diabetic nephropathy Lupus nephritis Pathophysiology Traditional Chinese medicine Immunity Pathogenesis Mechanism |
| ISSN号 | 2211-3835 |
| DOI | 10.1016/j.apsb.2023.11.006 |
| 通讯作者 | Guo, De-an(daguo@simm.ac.cn) |
| 英文摘要 | Immune -related nephropathy (IRN) refers to immune -response -mediated glomerulonephritis and is the main cause of end -stage renal failure. The pathogenesis of IRN is not fully understood; therefore, treatment is challenging. Traditional Chinese medicines (TCMs) have potent clinical effects in the treatment of the IRN conditions immunoglobulin A nephropathy, lupus nephropathy, and diabetic nephropathy. The underlying mechanisms mainly include its inhibition of inflammation; improvements to renal interstitial fibrosis, oxidative stress, autophagy, apoptosis; and regulation of immunity. In this review, we summarize the clinical symptoms of the three IRN subtypes and the use of TCM prescriptions, herbs, and bioactive compounds in treating IRN, as well as the potential mechanisms, intending to provide a reference for the future study of TCM as IRN treatments. (c) 2024 The Authors. Published by Elsevier B.V. on behalf of Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. This is an open access article under the CC BY -NCND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| WOS关键词 | AMELIORATES DIABETIC-NEPHROPATHY ; PATTERN-RECOGNITION RECEPTORS ; SYSTEMIC-LUPUS-ERYTHEMATOSUS ; IMMUNOGLOBULIN-A NEPHROPATHY ; RENAL OXIDATIVE STRESS ; HIGH-FAT DIET ; IGA NEPHROPATHY ; PODOCYTE APOPTOSIS ; NLRP3 INFLAMMASOME ; SIGNALING PATHWAY |
| 资助项目 | Qi-Huang Chief Scientist Project of National Administration of Traditional Chinese Medicine ; Key Program of National Natural Science Foundation of China[82130111] ; National Natural Science Foundation of China[32141005] ; National Natural Science Foundation of China[AOPWY66b5a] ; National Natural Science Foundation of China[WTAOO39edd] ; National Natural Science Foundation of China[AROOS03afd] ; National Natural Science Foundation of China[YSATU1760c] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001154147600001 |
| 出版者 | INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309076]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Guo, De-an |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Res Ctr TCM Standardizat Technol, Shanghai 201203, Peoples R China 2.Nanjing Univ Chinese Med, Sch Pharm, Nanjing 210023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Pu,Yao, Changliang,Guo, De-an. Traditional Chinese medicine for the treatment of immune-related nephropathy: A review[J]. ACTA PHARMACEUTICA SINICA B,2024,14(1):38-66. |
| APA | Jiang, Pu,Yao, Changliang,&Guo, De-an.(2024).Traditional Chinese medicine for the treatment of immune-related nephropathy: A review.ACTA PHARMACEUTICA SINICA B,14(1),38-66. |
| MLA | Jiang, Pu,et al."Traditional Chinese medicine for the treatment of immune-related nephropathy: A review".ACTA PHARMACEUTICA SINICA B 14.1(2024):38-66. |
入库方式： OAI收割
来源：上海药物研究所
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