Formyl phloroglucinol meroterpenoids from the leaves of Eucalyptus globulus subsp. maidenii and their ATP-citrate lyase inhibitory activities
文献类型:期刊论文
作者 | Hu, Zhu3; Liu, Yi-Nan1,3; Yu, Mei-Hua3; Hou, Ai -Jun2,3; Li, Jing-Ya1; Li, Ying-Xia3; Lei, Chun3 |
刊名 | FITOTERAPIA |
出版日期 | 2024-03-01 |
卷号 | 173页码:6 |
ISSN号 | 0367-326X |
关键词 | Eucalyptus globulus subsp. maidenii Meroterpenoids ATP-citrate lyase |
DOI | 10.1016/j.fitote.2023.105813 |
通讯作者 | Li, Jing-Ya(jyli@simm.ac.cn) ; Li, Ying-Xia(liyx417@fudan.edu.cn) ; Lei, Chun(chunlei@fudan.edu.cn) |
英文摘要 | Three new formyl phloroglucinol meroterpenoids, eumaidials A -C (1-3), were isolated from the leaves of Eucalyptus globulus subsp. maidenii, along with ten known analogues (4-13). Their chemical structures were determined by various spectral data and electronic circular dichroism calculations. Eumaidial A (1) is the first beta-caryophyllene-based formyl phloroglucinol meroterpenoids from the genus Eucalyptus. Compounds 1-4 and 10 exhibited ATP -citrate lyase inhibitory activities, and compounds 2 and 3 suppressed the hepatocyte lipogenesis. |
WOS关键词 | BIOMIMETIC SYNTHESIS ; SESQUITERPENOIDS ; PRINCIPLES ; LABILL ; FRUITS |
资助项目 | National Natural Science Foundation of China[82073717] |
WOS研究方向 | Pharmacology & Pharmacy |
语种 | 英语 |
出版者 | ELSEVIER |
WOS记录号 | WOS:001161119700001 |
源URL | [http://119.78.100.183/handle/2S10ELR8/309210] |
专题 | 中国科学院上海药物研究所 |
通讯作者 | Li, Jing-Ya; Li, Ying-Xia; Lei, Chun |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China 3.Fudan Univ, Sch Pharm, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Hu, Zhu,Liu, Yi-Nan,Yu, Mei-Hua,et al. Formyl phloroglucinol meroterpenoids from the leaves of Eucalyptus globulus subsp. maidenii and their ATP-citrate lyase inhibitory activities[J]. FITOTERAPIA,2024,173:6. |
APA | Hu, Zhu.,Liu, Yi-Nan.,Yu, Mei-Hua.,Hou, Ai -Jun.,Li, Jing-Ya.,...&Lei, Chun.(2024).Formyl phloroglucinol meroterpenoids from the leaves of Eucalyptus globulus subsp. maidenii and their ATP-citrate lyase inhibitory activities.FITOTERAPIA,173,6. |
MLA | Hu, Zhu,et al."Formyl phloroglucinol meroterpenoids from the leaves of Eucalyptus globulus subsp. maidenii and their ATP-citrate lyase inhibitory activities".FITOTERAPIA 173(2024):6. |
入库方式: OAI收割
来源:上海药物研究所
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