Personalized functional network mapping for autism spectrum disorder and attention-deficit/hyperactivity disorder
文献类型：期刊论文
| 作者 | Zhang, Jiang5; Zhang, Zhiwei5 ; Sun, Hui5; Ma, Yingzi3,4; Yang, Jia3,4; Chen, Kexuan2; Yu, Xiaohui3,4; Qin, Tianwei5; Zhao, Tianyu5; Zhang, Jingyue5
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| 刊名 | TRANSLATIONAL PSYCHIATRY
 |
| 出版日期 | 2024-02-12 |
| 卷号 | 14期号:1页码:11 |
| ISSN号 | 2158-3188 |
| DOI | 10.1038/s41398-024-02797-z |
| 通讯作者 | Wang, Jiaojian(jiaojianwang@uestc.edu.cn) |
| 英文摘要 | Autism spectrum disorder (ASD) and Attention-deficit/hyperactivity disorder (ADHD) are two typical neurodevelopmental disorders that have a long-term impact on physical and mental health. ASD is usually comorbid with ADHD and thus shares highly overlapping clinical symptoms. Delineating the shared and distinct neurophysiological profiles is important to uncover the neurobiological mechanisms to guide better therapy. In this study, we aimed to establish the behaviors, functional connectome, and network properties differences between ASD, ADHD-Combined, and ADHD-Inattentive using resting-state functional magnetic resonance imaging. We used the non-negative matrix fraction method to define personalized large-scale functional networks for each participant. The individual large-scale functional network connectivity (FNC) and graph-theory-based complex network analyses were executed and identified shared and disorder-specific differences in FNCs and network attributes. In addition, edge-wise functional connectivity analysis revealed abnormal edge co-fluctuation amplitude and number of transitions among different groups. Taken together, our study revealed disorder-specific and -shared regional and edge-wise functional connectivity and network differences for ASD and ADHD using an individual-level functional network mapping approach, which provides new evidence for the brain functional abnormalities in ASD and ADHD and facilitates understanding the neurobiological basis for both disorders. |
| WOS关键词 | BRAIN ; CONNECTIVITY ; CHILDREN |
| 资助项目 | National Science Foundation[62176044] ; Natural Science Foundation of Yunnan Province[202102AA100053] ; Yunnan Fundamental Research Projects[202201BE070001-004] ; Sichuan Science and Technology Program[2018TJPT0008] |
| WOS研究方向 | Psychiatry |
| 语种 | 英语 |
| 出版者 | SPRINGERNATURE |
| WOS记录号 | WOS:001161483500002 |
| 资助机构 | National Science Foundation ; Natural Science Foundation of Yunnan Province ; Yunnan Fundamental Research Projects ; Sichuan Science and Technology Program |
| 源URL | [http://ir.ia.ac.cn/handle/173211/55577]  |
| 专题 | 脑图谱与类脑智能实验室 |
| 通讯作者 | Wang, Jiaojian |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China 2.Kunming Univ Sci & Technol, Med Sch, Kunming, Peoples R China 3.Yunnan Key Lab Primate Biomed Res, Kunming, Yunnan, Peoples R China 4.Kunming Univ Sci & Technol, Inst Primate Translat Med, State Key Lab Primate Biomed Res, Kunming, Peoples R China 5.Sichuan Univ, Coll Elect Engn, Chengdu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jiang,Zhang, Zhiwei,Sun, Hui,et al. Personalized functional network mapping for autism spectrum disorder and attention-deficit/hyperactivity disorder[J]. TRANSLATIONAL PSYCHIATRY,2024,14(1):11. |
| APA | Zhang, Jiang.,Zhang, Zhiwei.,Sun, Hui.,Ma, Yingzi.,Yang, Jia.,...&Wang, Jiaojian.(2024).Personalized functional network mapping for autism spectrum disorder and attention-deficit/hyperactivity disorder.TRANSLATIONAL PSYCHIATRY,14(1),11. |
| MLA | Zhang, Jiang,et al."Personalized functional network mapping for autism spectrum disorder and attention-deficit/hyperactivity disorder".TRANSLATIONAL PSYCHIATRY 14.1(2024):11. |
入库方式： OAI收割
来源：自动化研究所
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