First clinical applications for the NIR-II imaging with ICG in microsurgery
文献类型：期刊论文
| 作者 | Wu, Yifan1; Suo, Yongkuan2; Wang, Zheng1; Yu, Yifeng1; Duan, Shuang2; Liu, Hongguang2; Qi, Baiwen1; Jian, Chao1; Hu, Xiang1; Zhang, Dong1 |
| 刊名 | FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
 |
| 出版日期 | 2022-10-18 |
| 卷号 | 10页码:1042546 |
| ISSN号 | 2296-4185 |
| 关键词 | indocyanine green (ICG) near-infrared II (NIR-II) imaging fluorescenceguided surgery vascular anastomosis flap reconstruction |
| DOI | 10.3389/fbioe.2022.1042546 |
| 文献子类 | Article |
| 英文摘要 | In microsurgery, it is always difficult to accurately identify the blood supply with ease, such as vascular anastomosis, digit replantation, skin avulsion reconstruction and flap transplantation. Near-infrared window I (NIR-I, 700-900 nm) imaging has many clinical applications, whereas near-infrared window II (NIR-II, 1,000-1700 nm) imaging has emerged as a highly promising novel optical imaging modality and used in a few clinical fields recently, especially its penetration distance and noninvasive characteristics coincide with the needs of microsurgery. Therefore, a portable NIR-II imaging instrument and the Food and Drug Administration (FDA) approved indocyanine green (ICG) were used to improve the operation efficiency in microsurgery of 39 patients in this study. The anastomotic vessels and the salvaged distal limbs were clearly visualized after intravenous injection of ICG. The technique enabled identification of perforator vessels and estimation of perforator areas prior to the flap obtention and made it easier to monitor the prognosis. Overall, this study highlights the use of the portable NIR- II imaging with ICG as an operative evaluation tool can enhance the safety and accuracy of microsurgery. |
| WOS关键词 | NEAR-INFRARED ANGIOGRAPHY ; ANTEROLATERAL THIGH FLAP ; FLUORESCENCE ; DOPPLER ; RECONSTRUCTION ; MANAGEMENT ; PERFUSION ; VESSELS |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Engineering |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| WOS记录号 | WOS:000878498700001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309298]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Yu, Aixi; Cheng, Zhen |
| 作者单位 | 1.Wuhan Univ, Dept Orthoped Trauma & Microsurg, Zhongnan Hosp, Wuhan, Peoples R China; 2.Northeastern Univ, Inst Mol Med, Joint Lab Mol Med, Shenyang, Liaoning, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai, Peoples R China; 4.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Yifan,Suo, Yongkuan,Wang, Zheng,et al. First clinical applications for the NIR-II imaging with ICG in microsurgery[J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,2022,10:1042546. |
| APA | Wu, Yifan.,Suo, Yongkuan.,Wang, Zheng.,Yu, Yifeng.,Duan, Shuang.,...&Cheng, Zhen.(2022).First clinical applications for the NIR-II imaging with ICG in microsurgery.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,10,1042546. |
| MLA | Wu, Yifan,et al."First clinical applications for the NIR-II imaging with ICG in microsurgery".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 10(2022):1042546. |
入库方式： OAI收割
来源：上海药物研究所
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