Engineering Nanorobots for Tumor-Targeting Drug Delivery: From Dynamic Control to Stimuli-Responsive Strategy
文献类型：期刊论文
| 作者 | Huang, Lujia1,2; Chen, Fangmin1,2; Lai, Yi1; Xu, Zhiai3; Yu, Haijun1,2
|
| 刊名 | CHEMBIOCHEM
 |
| 出版日期 | 2021-12-10 |
| 卷号 | 22期号:24页码:3369-3380 |
| ISSN号 | 1439-4227 |
| 关键词 | dynamic control nanorobots stimuli-responsive strategy tumor-targeting drug delivery |
| DOI | 10.1002/cbic.202100347 |
| 文献子类 | Review |
| 英文摘要 | Nanotechnology has been widely applied to the fabrication of drug delivery systems in the past decades. Recently, with the progress made in microfabrication approaches, nanorobots are steadily becoming a promising means for tumor-targeting drug delivery. In general, nanorobots can be divided into two categories: nanomotors and stimuli-responsive nanorobots. Nanomotors are nanoscale systems with the ability to convert surrounding energies into mechanical motion, whereas stimuli-responsive nanorobots are featured with activatable capacity in response to various endogenous and exogenous stimulations. In this minireview, the dynamic control of nanomotors and the rational design of stimuli-responsive nanorobots are overviewed, with particular emphasis on their contribution to tumor-targeting therapy. Moreover, challenges and perspectives associated with the future development of nanorobots are presented. |
| WOS关键词 | CANCER ; NANOPARTICLES ; NANOMOTORS ; PEMBROLIZUMAB ; NANOCARRIERS ; MECHANISMS ; RESISTANCE ; LIPOSOMES ; ANTI-PD-1 ; RELEASE |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000695582100001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309368]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Lai, Yi; Yu, Haijun |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res & Ctr Pharmaceut, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 3.East China Normal Univ, Sch Chem & Mol Engn, Shanghai 200241, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Lujia,Chen, Fangmin,Lai, Yi,et al. Engineering Nanorobots for Tumor-Targeting Drug Delivery: From Dynamic Control to Stimuli-Responsive Strategy[J]. CHEMBIOCHEM,2021,22(24):3369-3380. |
| APA | Huang, Lujia,Chen, Fangmin,Lai, Yi,Xu, Zhiai,&Yu, Haijun.(2021).Engineering Nanorobots for Tumor-Targeting Drug Delivery: From Dynamic Control to Stimuli-Responsive Strategy.CHEMBIOCHEM,22(24),3369-3380. |
| MLA | Huang, Lujia,et al."Engineering Nanorobots for Tumor-Targeting Drug Delivery: From Dynamic Control to Stimuli-Responsive Strategy".CHEMBIOCHEM 22.24(2021):3369-3380. |
入库方式： OAI收割
来源：上海药物研究所
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