中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 新药研究国家重点实验室
Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides

文献类型：期刊论文

作者Dai, Tianzi1,2; Cui, Chen1,2; Qi, Xueyu1; Cheng, Yanshu1; He, Qian1; Zhang, Xiaofei1; Luo, Xiaomin1,2; Yang, Chunhao1,2
刊名ORGANIC & BIOMOLECULAR CHEMISTRY
出版日期2020-08-21
卷号18期号:31页码:6162-6170
ISSN号1477-0520
DOI10.1039/d0ob01019g
文献子类Article
英文摘要A facile and efficient strategy to synthesize substituted thiazolesviaa cascade reaction from chromone derivatives and thioamides in an environmentally benign medium was developed. This cascade reaction involves a Michael addition/intramolecular cyclization process and a broad scope of reversed regioselectivity products was prepared in a short reaction time with excellent yields. The reversed regioselectivity was also explained by DFT calculations.
WOS关键词ONE-POT SYNTHESIS ; CARBONYL-COMPOUNDS ; INHIBITORS ; IMIDAZOPYRIDINES ; CHEMISTRY ; MUSCARINE ; CHROMONES ; ANALOGS ; KETONES ; OXAZOLE
WOS研究方向Chemistry
语种英语
出版者ROYAL SOC CHEMISTRY
WOS记录号WOS:000558540500020
源URL[http://119.78.100.183/handle/2S10ELR8/309410]  
专题新药研究国家重点实验室
通讯作者Luo, Xiaomin; Yang, Chunhao
作者单位1.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Matena Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China;
2.Univ Chinese Acad Sci, Sch Pharm, 19A Yuquan Rd, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Dai, Tianzi,Cui, Chen,Qi, Xueyu,et al. Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2020,18(31):6162-6170.
APA Dai, Tianzi.,Cui, Chen.,Qi, Xueyu.,Cheng, Yanshu.,He, Qian.,...&Yang, Chunhao.(2020).Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides.ORGANIC & BIOMOLECULAR CHEMISTRY,18(31),6162-6170.
MLA Dai, Tianzi,et al."Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides".ORGANIC & BIOMOLECULAR CHEMISTRY 18.31(2020):6162-6170.

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。