New sesquiterpenoids from the South China Sea soft corals Clavularia viridis and Lemnalia flava
文献类型：期刊论文
| 作者 | Wu, Qihao1,2,3; Gao, Yuan1; Zhang, Meng-Meng1; Sheng, Li1; Li, Jia1 ; Li, Xu-Wen1; Wang, Hong2; Guo, Yue-Wei1,2,3
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| 刊名 | BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
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| 出版日期 | 2019-03-15 |
| 卷号 | 15页码:695-702 |
| 关键词 | Clavularia viridis Lemnalia flava NF-kappa B PTP1B sesquiterpenoid soft coral terpenes |
| ISSN号 | 1860-5397 |
| DOI | 10.3762/bjoc.15.64 |
| 文献子类 | Article |
| 英文摘要 | A detailed chemical investigation of the South China Sea soft corals Clavularia viridis and Lemnalia flava yielded four new halogenated laurane-type sesquiterpenoids, namely, isobromolaurenisol (1), clalaurenol A (2), ent-laurenisol (3), clalaurenol B (4), and the new aromadendrane-type sesquiterpenoid claaromadendrene (6), together with three known sesquiterpenoids (5, 7, and 8). Their structures were determined by extensive spectroscopic analysis and by comparison with the previously reported analogues. In a bioassay, compounds 1, 2 and 4 exhibited interesting inhibitory activities in vitro against PTP1B and NF-kappa B. |
| WOS关键词 | TRINOR-GUAIANE SESQUITERPENE ; DITERPENOIDS ; CONSTITUENTS ; METABOLITES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000463329200001 |
| 出版者 | BEILSTEIN-INSTITUT |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309434]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Wang, Hong; Guo, Yue-Wei |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd,Hitech Pk, Shanghai 201203, Peoples R China; 2.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China; 3.Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Qihao,Gao, Yuan,Zhang, Meng-Meng,et al. New sesquiterpenoids from the South China Sea soft corals Clavularia viridis and Lemnalia flava[J]. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,2019,15:695-702. |
| APA | Wu, Qihao.,Gao, Yuan.,Zhang, Meng-Meng.,Sheng, Li.,Li, Jia.,...&Guo, Yue-Wei.(2019).New sesquiterpenoids from the South China Sea soft corals Clavularia viridis and Lemnalia flava.BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,15,695-702. |
| MLA | Wu, Qihao,et al."New sesquiterpenoids from the South China Sea soft corals Clavularia viridis and Lemnalia flava".BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY 15(2019):695-702. |
入库方式： OAI收割
来源：上海药物研究所
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