Ultrasensitive fluorescence detection of gonyautoxins in seawater using a novel molecularly imprinted nanoprobe
文献类型：期刊论文
| 作者 | Xu, Huan3; Lian, Ziru3; Hao, Xiaochen3; Li, Fang3; Yu, Ren-Cheng1,2 |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2024-02-20 |
| 卷号 | 912页码:11 |
| ISSN号 | 0048-9697 |
| 关键词 | Gonyautoxins Fluorescence enhancement nanoprobe Seawater Ultrasensitive detection Surface molecular imprinting |
| DOI | 10.1016/j.scitotenv.2023.169056 |
| 通讯作者 | Lian, Ziru(yoyo-lzr@hotmail.com) |
| 英文摘要 | Gonyautoxins (GTXs), a group of potent neurotoxins belonging to paralytic shellfish toxins (PSTs), are often associated with harmful algal blooms of toxic dinoflagellates in the sea and represent serious health and ecological concerns worldwide. In the study, a highly selective and sensitive fluorescence nanoprobe was con-structed based on photoinduced electron transfer recognition mechanism to rapidly detect GTXs in seawater, using specific entrapment of molecularly imprinted polymers (MIPs) combined with fluorescence analyses. The green emissive fluorescein isothiocyanate was grafted in a silicate matrix as a signal transducer and fluorescence intensity of the nanoprobe with a core-shell structure exhibited a strong enhancement due to efficient analyte blockage in a short response time. Under optimal conditions, the developed MIPs nanoprobe presented an excellent analytical performance for spiked seawater samples including a recovery from 94.44 % to 98.23 %, a linear range between 0.018 nmol L-1 and 0.36 nmol L-1, as well as good accuracy. Furthermore, the method had extremely high sensitivity, with limit of detection obtained as 0.005 nmol L-1 for GTXs and GTX2/3. Finally, the nanoprobe was applied for the determination of GTXs in seven natural seawater samples with GTXs mixture (0.035-0.058 nmol L-1) or single GTX2/3 (0.033-0.050 nmol L-1), and the results agreed well with those of a UPLC-MS/MS method. The findings of our study suggest that the constructed MIPs-based fluorescence enhancement nanoprobe was suitable for rapid, selective and ultrasensitive detection of GTXs, particular GTX2/ 3, in natural seawater samples. |
| WOS关键词 | PARALYTIC SHELLFISH TOXINS ; SOLID-PHASE EXTRACTION ; LIQUID-CHROMATOGRAPHY ; POLYMER ; OXIDATION ; BLOOMS |
| 资助项目 | Joint Funds of the National Natural Science Foundation of China[U22A20583] ; Taishan Scholars Program |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:001133920800001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/184227]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Lian, Ziru |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shandong Univ, Marine Coll, Weihai 264209, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Huan,Lian, Ziru,Hao, Xiaochen,et al. Ultrasensitive fluorescence detection of gonyautoxins in seawater using a novel molecularly imprinted nanoprobe[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2024,912:11. |
| APA | Xu, Huan,Lian, Ziru,Hao, Xiaochen,Li, Fang,&Yu, Ren-Cheng.(2024).Ultrasensitive fluorescence detection of gonyautoxins in seawater using a novel molecularly imprinted nanoprobe.SCIENCE OF THE TOTAL ENVIRONMENT,912,11. |
| MLA | Xu, Huan,et al."Ultrasensitive fluorescence detection of gonyautoxins in seawater using a novel molecularly imprinted nanoprobe".SCIENCE OF THE TOTAL ENVIRONMENT 912(2024):11. |
入库方式： OAI收割
来源：海洋研究所
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